Butethamate
Structural Formula Vector Image
Title: Butethamate
CAS Registry Number: 14007-64-8
CAS Name: Benzeneacetic acid a-ethyl-2-(diethylamino)ethyl ester
Additional Names: 2-phenylbutyric acid 2-(diethylamino)ethyl ester; b-diethylaminoethyl ethylphenylacetate; 2-diethylaminoethyl 2-phenylbutyrate
Molecular Formula: C16H25NO2
Molecular Weight: 263.38
Percent Composition: C 72.96%, H 9.57%, N 5.32%, O 12.15%
Literature References: Prepn: Di Paco, Tauro, Farmaco Ed. Sci. 11, 540 (1956); CH 291375 (1953 to AG Hommel's Haematogen) and CH 292596 (1953 to Chem. Fabrik "PARA"), C.A. 49, 2505a,c (1955). Pharmacology: Jordan, Arzneim.-Forsch. 8, 716 (1958); Fleisch et al., ibid. 11, 1119 (1961).
Properties: bp11 167-169°. nD20 1.4909.
Boiling point: bp11 167-169°
Index of refraction: nD20 1.4909
 
Derivative Type: Citrate
CAS Registry Number: 3639-12-1
Trademarks: Abuphenine; Convenil (Hommel); Hicoseen (Klimitschek); Phenesin; Phenetin (Alpinapharm)
Molecular Formula: C16H25NO2.C6H8O7
Molecular Weight: 455.50
Percent Composition: C 58.01%, H 7.30%, N 3.08%, O 31.61%
Properties: Crystals from abs alcohol, mp 109-110°. Freely sol in water, alcohol.
Melting point: mp 109-110°
 
Therap-Cat: Antitussive.
Keywords: Antitussive.

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