Structural Formula Vector Image
Title: Cyclazocine
CAS Registry Number: 3572-80-3
CAS Name: 3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
Manufacturers' Codes: Win-20740; NSC-107429
Molecular Formula: C18H25NO
Molecular Weight: 271.40
Percent Composition: C 79.66%, H 9.28%, N 5.16%, O 5.90%
Literature References: Analgesic with mixed narcotic agonist-antagonist properties. Prepn: Archer, BE 611000 (1962 to Sterling Drug), C.A. 58, 2439c (1963). Crystal structure: I. L. Karle et al., Acta Crystallogr. B25, 1469 (1969). Supraspinal analgesic effects: S. Sasson, C. Kornetsky, Life Sci. 38, 21 (1986). Evaluation in anorexia and motor disruption in rats: J. W. Henck et al., Pharmacol. Biochem. Behav. 22, 671 (1985). Determn by HPLC: I. Jane, A. McKinnon, J. Chromatogr. 323, 191 (1985). Review of use in treatment of opiate addiction: M. J. Goldstein, Int. J. Addict. 15, 939 (1980).
Properties: Crystals from methanol, mp 201-204°.
Melting point: mp 201-204°
Therap-Cat: Narcotic antagonist.
Keywords: Narcotic Antagonist.

Other Monographs:
CrotethamideEthyl tert-Butyl EtherIodine MonochloridePropacetamol
AnhalonineChlormadinone AcetateGallium TrifluorideLetrozole
DichlormidChloroacetanilideRisperidoneSalicyl Alcohol
Pangamic AcidPramoxineTurmericTartronic Acid
©2006-2023 DrugFuture->Chemical Index Database