Bisoxatin Acetate
Structural Formula Vector Image
Title: Bisoxatin Acetate
CAS Registry Number: 14008-48-1
CAS Name: 2,2-Bis[4-(acetyloxy)phenyl]-2H-1,4-benzoxazin-3(4H)-one
Additional Names: 2,2-bis(4-acetoxyphenyl)-3-oxo-2,3-dihydrobenz-1,4-oxazine
Manufacturers' Codes: Wy-8138
Trademarks: Laxonalin; Maratan (Ravizza); Talsis (Wyeth); Tasis (Wyeth)
Molecular Formula: C24H19NO6
Molecular Weight: 417.41
Percent Composition: C 69.06%, H 4.59%, N 3.36%, O 23.00%
Literature References: Prepd from 2,2-dichloro-3-oxo-2,3-dihydrobenz-1,4-oxazine and phenylacetate or by acetylation of the diphenol: Seeger, US 3006917 (1961 to Thomae). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Crystals from ethanol, mp 190°. LD50 orally in rats, mice: 8000, >10,000 mg/kg (Goldenthal).
Melting point: mp 190°
Toxicity data: LD50 orally in rats, mice: 8000, >10,000 mg/kg (Goldenthal)
Therap-Cat: Cathartic.
Keywords: Laxative/Cathartic.

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