Vinbarbital Sodium
Structural Formula Vector Image
Title: Vinbarbital Sodium
CAS Registry Number: 125-44-0
CAS Name: 5-Ethyl-5-(1-methyl-1-butenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Additional Names: 5-ethyl-5-(1-methyl-1-butenyl)barbituric acid sodium salt; sodium 5-ethyl-5-(1-methyl-1-butenyl)barbiturate
Trademarks: Delvinal Sodium (Merck & Co.)
Molecular Formula: C11H15N2NaO3
Molecular Weight: 246.24
Percent Composition: C 53.65%, H 6.14%, N 11.38%, Na 9.34%, O 19.49%
Literature References: Prepn: Cope, Hancock, J. Am. Chem. Soc. 61, 776 (1939); Cope, US 2187703 (1940 to Sharp & Dohme). Pharmacology and toxicity: J. P. Hendrix, J. Pharmacol. Exp. Ther. 68, 22 (1940).
Properties: Hygroscopic crystals, bitter taste. Slightly sol in ether and chloroform. A 1% aq soln is alkaline to phenolphthalein and has a pH between 8.5 and 9.5. Unbuffered aq solns are unstable. LD50 orally in rats: 130 mg/kg (Hendrix).
Toxicity data: LD50 orally in rats: 130 mg/kg (Hendrix)
Derivative Type: Free acid
Molecular Formula: C11H15N2O3
Molecular Weight: 223.25
Percent Composition: C 59.18%, H 6.77%, N 12.55%, O 21.50%
Properties: mp 161-163°.
Melting point: mp 161-163°
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Therap-Cat-Vet: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.

Other Monographs:
Folinic AcidMagnesium ThiosulfateButhionine SulfoximineViehe's Salt
Ammonium HexafluorophosphateCyclodrineL-AsparaginaseEPN
Croscarmellose SodiumOctodrineTobramycinIsoamyl Nitrate
©2006-2023 DrugFuture->Chemical Index Database