Structural Formula Vector Image
Title: Mepiprazole
CAS Registry Number: 20326-12-9
CAS Name: 1-(3-Chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine
Additional Names: 3-[2-(N¢-m-chlorophenylpiperazino)ethyl]-5-methylpyrazole
Manufacturers' Codes: EMD-16923
Molecular Formula: C16H21ClN4
Molecular Weight: 304.82
Percent Composition: C 63.04%, H 6.94%, Cl 11.63%, N 18.38%
Literature References: Psychotropic agent with CNS-depressant effects. Prepn: V. Koppe et al., GB 1124710; eidem, US 3491097 (1968, 1970 both to E. Merck); eidem, Eur. J. Med. Chem. 10, 154, 162 (1975). Pharmacological study: M. A. Ruch-Monachon et al., Arch. Int. Pharmacodyn. Ther. 219, 326 (1976). Effects on brain biogenic amine metabolism: C. Seyfried et al., Arzneim.-Forsch. 26, 1088 (1976). EEG effects in rabbits: S. Watanabe et al., ibid. 29, 274 (1979).
Properties: Crystals, mp 106°.
Melting point: mp 106°
Derivative Type: Dihydrochloride
CAS Registry Number: 20344-15-4
Manufacturers' Codes: H-4007
Trademarks: Psigodal (Merck KGaA)
Molecular Formula: C16H21ClN4.2HCl
Molecular Weight: 377.74
Percent Composition: C 50.87%, H 6.14%, Cl 28.16%, N 14.83%
Properties: Cryst from ethanol, mp 234°.
Melting point: mp 234°
Therap-Cat: Tranquilizer.
Status: This monograph has been retired and is no longer subject to revision or update.

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