Structural Formula Vector Image
Title: Carbarsone
CAS Registry Number: 121-59-5
CAS Name: [4-[(Aminocarbonyl)amino]phenyl]arsonic acid
Additional Names: N-carbamoylarsanilic acid; p-ureidobenzenearsonic acid; N-carbamylarsanilic acid; p-carbamidobenzenearsonic acid; 4-ureido-1-phenylarsonic acid; 4-carbamylaminophenylarsonic acid; p-arsonophenylurea
Trademarks: Amabevan; Ameban; Amibiarson; Arsambide; Carb-O-Sep (Rohm & Haas); Histocarb (Rohm & Haas); Fenarsone; Leucarsone; Aminarsone; Amebarsone (Lilly)
Molecular Formula: C7H9AsN2O4
Molecular Weight: 260.08
Percent Composition: C 32.33%, H 3.49%, As 28.81%, N 10.77%, O 24.61%
Literature References: Prepd from the sodium salt of arsanilic acid by treatment with potassium cyanate or cyanogen bromide: DE 213155; Stickings, J. Chem. Soc. 1928, 3131; from arsanilic acid by treatment with phosgene: Nakatsu, Kawase, Annu. Rep. Takamine Lab. 8, 44-47 (1956); JP 58 4418 (1958 to Sankyo). Toxicity study: N. A. David et al., Proc. Soc. Exp. Biol. Med. 29, 125 (1931).
Properties: White powder. mp 174°. Slightly sol in water, alcohol; sol in solns of alkali hydroxides and carbonates. The satd aq soln is acid to litmus. Nearly insol in ether or chloroform.
Melting point: mp 174°
Therap-Cat: Antiamebic.
Therap-Cat-Vet: Antihistomonad in turkeys.
Keywords: Antiamebic.

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