Structural Formula Vector Image
Title: Arteether
CAS Registry Number: 75887-54-6
CAS Name: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
Additional Names: dihydroartemisinin ethyl ether; dihydroqinghaosu ethyl ether; artemotil
Manufacturers' Codes: SM-227
Molecular Formula: C17H28O5
Molecular Weight: 312.40
Percent Composition: C 65.36%, H 9.03%, O 25.61%
Literature References: Derivative of artemisinin, q.v. Prepn: Y. Li et al., Acta Pharm. Sin. 16, 429 (1981). Synthesis and antimalarial activity: China Cooperative Research Group on Qinghaosu, J. Tradit. Chin. Med. 2, 9 (1982); A. Brossi et al., J. Med. Chem. 31, 645 (1988).
Properties: White crystalline solid, mp 80-82°. [a]D21 +154.5° (c = 1.0 in CHCl3).
Melting point: mp 80-82°
Optical Rotation: [a]D21 +154.5° (c = 1.0 in CHCl3)
Therap-Cat: Antimalarial.
Keywords: Antimalarial.

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