4-Pregnene-17alpha,20beta,21-triol-3,11-dione
Structural Formula Vector Image
Title: 4-Pregnene-17a,20b,21-triol-3,11-dione
CAS Registry Number: 116-59-6
CAS Name: (20R)-17,20,21-Trihydroxypregn-4-ene-3,11-dione
Additional Names: Reichstein's substance U
Molecular Formula: C21H30O5
Molecular Weight: 362.46
Percent Composition: C 69.59%, H 8.34%, O 22.07%
Literature References: Isoln from adrenal glands: Reichstein, von Euw, Helv. Chim. Acta 24, 247E (1941).
Properties: Clusters of needles from acetone + ether, mp 208-209°.
Melting point: mp 208-209°
 
Derivative Type: 20,21-Diacetate
Molecular Formula: C25H34O7
Molecular Weight: 446.53
Percent Composition: C 67.24%, H 7.67%, O 25.08%
Properties: Pointed needles from acetone + ether or chloroform + ether, mp 253°. [a]D21 +178.5° (c = 0.924 in acetone). uv max (alc): 239 nm (log e 4.1). Less sol than the 20,21-diacetate of 4-pregnene-11b,17a,20,21-tetrol-3-one.
Melting point: mp 253°
Optical Rotation: [a]D21 +178.5° (c = 0.924 in acetone)
Absorption maximum: uv max (alc): 239 nm (log e 4.1)

Other Monographs:
Gallium ArsenidePotassium ArsenateCalmodulinCinmethylin
Ammonium Ferric ChromateCefazedoneOrlon®Thioacetaldehyde
Glyoxylic AcidCorypalmine3-Pyridineacetic AcidSodium Selenate
Nickel FluorideXenazoic AcidMaprotilineMitoguazone
©2006-2020 DrugFuture->Chemical Index Database