美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Avanafil	Tablet	II (Paddle)	50	Simulated gastric fluid without pepsin.	900	5, 10, 15, 20 and 30	2015/04/02
Avapritinib	Tablet	II (Paddle)	75	0.05 M Sodium Acetate Buffer, pH 5.0 containing 0.5% w/v cetyl trimethylammonium bromide (CTAB)	900	5, 10, 15, 20, 30, 45, 60, 90 and 120	2022/05/12
Axitinib	Tablet	II (Paddle)	75	0.01 N HCl	900	5, 15, 30, 45 and 60	2014/08/14
Azacitidine	Tablet	II (Paddle)	75	50 mM phosphate buffer, pH 6.8	500	5, 10, 15, 20, 30 and 45	2023/11/30
Azacitidine	Injectable Suspension			Develop a dissolution method			2008/09/03
Azathioprine	Tablet			Develop a dissolution method			2024/01/03
Azilsartan Kamedoxomil	Tablet	II (Paddle)	50	Phosphate Buffer, pH 7.8 (deaerated)	900	5, 10, 15, 20, 30 and 45	2013/05/09
Azilsartan Kamedoxomil/Chlorthalidone	Tablet	II (Paddle)	50	Phosphate Buffer, pH 6.8 containing 1.0% Tween 80,	900	5, 10, 15, 20, 30 and 45	2013/05/09
Azithromycin	Suspension (Extended Release)	II (Paddle)	50	Phosphate Buffer, pH 6.0	900	15, 30, 45, 60, 120 and 180	2008/04/15
Azithromycin	Oral Suspension	II (Paddle)	50	Phosphate buffer, pH 6.0	900	10, 20, 30, and 45	2006/08/17
Azithromycin	Tablet			Refer to USP			2016/12/22
Azithromycin	Capsule			Refer to USP			2016/12/22
Baclofen	Suspension	II (Paddle)	25	0.01 N HCl	500	5, 10, 15, 30, 45 and 60	2024/05/31
Baclofen	Granules	II (Paddle)	50	0.01 N HCl	500	5, 10, 15 and 30	2024/02/05
Baclofen	Tablet			Refer to USP			2009/12/15
Baclofen	Tablet (Orally Disintegrating)	II (Paddle)	25	50 mM Acetate Buffer, pH 4.5	500 mL (10 mg) or 1000 mL (20mg)	5, 10, 15 and 30	2008/07/14
Baloxavir Marboxil	Tablet	II (paddle)	50	20 mg: Phosphate Buffer, pH 6.8 with 0.07% w/v (CTAB); 40 mg: Phosphate Buffer, pH 6.8 with 0.16% w/v CTAB; 80 mg: Phosphate Buffer, pH 6.8 with 0.40 w/v cetyltrimethylammonium bromide (CTAB)	900	5, 10, 15, 20, 30 and 45	2023/07/07
Baloxavir Marboxil	For Suspension	II (Paddle)	25	Phosphate Buffer, pH 6.8 containing 0.16% w/v cetyl trimethylammonium bromide (CTAB)	900	5, 10, 15, 20 and 30	2023/02/09
Balsalazide Disodium	Capsule	II (Paddle) with sinker	50	pH 6.8 buffer	900	10, 20, 30, and 45	2006/01/26
Balsalazide Disodium	Tablet			Develop a dissolution method			2023/09/15