美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Baricitinib	Tablet	II (Paddle)	75	Acetate buffer pH 4.5	900	5, 15, 30, 45	2023/03/30
Bedaquiline Fumarate	Tablet	I (Basket)	150	0.01 N HCl	900	10, 15, 20, 30 and 45	2013/06/06
Belzutifan	Tablet	II (Paddle)	50	50 mM potassium phosphate buffer at pH 6.5 with 68 mM potassium chloride (@37°C)	900	10, 15, 20, 30, 45 and 60	2023/07/07
Bempedoic Acid	Tablet	II (Paddle)	50	0.05 M Phosphate buffer, pH 6.6	900	5, 10, 15, 20 and 30	2021/08/19
Bempedoic Acid/Ezetimibe	Tablet	II (Paddle)	50	Bempedoic Acid: 0.05 M Phosphate buffer, pH 6.6; Ezetimibe: 0.05M Sodium Acetate Buffer pH 4.5 with 0.45% SLS	900	5, 10, 15, 20, 30, and 45	2021/08/19
Benazepril HCl	Tablet			Develop a dissolution method			2023/09/15
Benazepril HCl/Hydrochlorothiazide	Tablet	I (Basket)	100	0.1 N HCl	500	10, 20, 30 and 45	2004/01/16
Bendroflumethiazide/Nadolol	Tablet			Refer to USP			2007/07/25
Benzgalantamine Gluconate	Tablet, Delayed Release	I (Basket)	50	Acid Stage: 0.1N HCl; Buffer Stage: 0.05M Sodium Phosphate buffer pH 6.8 with 0.5% SDS	1000	Acid stage: 120; Buffer stage: 15, 20, 30, 45, 60 and 75	2025/06/23
Benzonatate	Capsule			Develop a dissolution method			2024/01/03
Benzoyl Peroxide; Clindamycin Phosphate	Gel			Develop a method to characterize in vitro release			2023/05/18
Benzphetamine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Bepridil HCl	Tablet	I (Basket)	100	0.1 N HCl	900	10, 20, 30, 45 and 60	2004/01/16
Berotralstat HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2023/02/09
Betamethasone Acetate/Betamethasone Sodium Phosphate	Injectable Suspension	IV (Flow through cell)	Flow @ 8 mL/min	0.05% SLS, pH 3.0 or Develop an in vitro release method using USP IV (Flow-Through Cell), and, if applicable, Apparatus II (Paddle) or any other appropriate method, for comparative evaluation by the Agency		5, 10, 15, 30, 45, 60, 90, 120, 180, 240, 300, and 360	2010/04/08
Bethanechol Chloride	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Bethanechol Chloride	Tablet			Refer to USP			2008/10/06
Betrixaban	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Bexagliflozin	Tablet	I (Basket)	50	0.1 N HCl	900	1, 3, 5, 8 and 10 hours	2024/05/31
Bexarotene	Capsule	II (Paddle)	50	Tier 1 Medium: 0.5% HDTMA in 0.05 M phosphate buffer, pH 7.5 Tier 2 Medium: 0.5% HDTMA in 0.05 M phosphate buffer, pH 7.5 with 0.05 g/L pancreatin enzyme	900	15, 30, 45 and 60	2006/08/17