美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Solifenacin Succinate	Suspension	II (Paddle)	50	0.1 N HCl	900	5, 10, 15, 20 and 30	2022/07/07
Solriamfetol HCl	Tablet	I (Basket)	100	0.1 N HCl	900	5, 10, 15, 20 and 30	2021/08/19
Sonidegib Phosphate	Capsule	II (Paddle) with sinker	75	Tier 1: 0.1 M HCl with 1.0% SDS; Tier II: Stage 1: 850 mL of 0.1 N HCl solution with pepsin [250’000 units/L]. Stage 2: After 10 minutes add 50 mL of 18% SDS in 0.1 N HCl	Tier 1: 900; Tier 2: Stage 1: 850 mL, Stage 2: 900 mL	15, 30, 45, 60, and 90	2016/03/17
Sorafenib Tosylate	Tablet	II (Paddle)	75	0.1 M HCl with 1% SDS	900	5, 10, 15, 20 and 30	2009/06/10
Sotagliflozin	Tablet			Develop a dissolution method			2024/08/05
Sotorasib	Tablet	II (Paddle)	75	120 mg: 50 mM phosphate buffer, pH 6.8 with 0.2% SLS; 320 mg: 50 mM phosphate buffer, pH 6.8 with 0.4% SDS	900	5,10,15, 20 and 30	2023/11/30
Sparsentan	Tablet	II (Paddle)	60	0.1 N HCl	1000	5, 10, 15, 20, 30, 45 and 60	2024/05/31
Spironolactone	Tablet			Refer to USP			2008/04/15
Stavudine	Capsule			Develop a dissolution method			2024/01/03
Succimer	Capsule	II (Paddle)	50	0.01 N Phosphoric Acid	900	10, 20, 30, 45, 60 and 90	2004/02/20
Sucralfate	Suspension	II (Paddle)	75	0.1N HCl/0.067 M KCl, pH 1.0	900	10, 20, 30 and 45	2006/03/04
Sucralfate	Tablet	II (Paddle)	75	0.1 N HCl/0.067 M KCl, pH 1.0	900	15, 30, 45, 60, 180, 240 and 480	2009/04/02
Sucroferric Oxyhydroxide	Tablet (Chewable)	II (Paddle)	50	0.1 N HCl	900	10, 15, 20, 30, 45 and 60	2017/11/02
Sufentanil Citrate	Tablet (Sublingual)	II (Paddle)	50	pH 4.5 Acetate Buffer	50	2, 4, 8, 12 and 15	2022/05/12
Sulfadiazine	Tablet			Refer to USP			2008/07/14
Sulfamethoxazole/Trimethoprim	Tablet			Refer to USP			2008/01/14
Sulfamethoxazole/Trimethoprim	Suspension	II (Paddle)	50	1 mL of 0.2 N HCl in water	900	10, 20, 30, 45, 60 and 90	2004/02/25
Sulfasalazine	Tablet			Refer to USP			2009/12/15
Sulfasalazine	Tablet (Delayed Release)			Refer to USP			2009/12/15
Sulfisoxazole Acetyl	Oral Suspension (Pediatric)	II (Paddle)	30	1% SLS in 0.1N HCl	900	15, 30, 45, 60 and 90	2006/08/17