美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Selinexor	Tablet	II (Paddle)	75	10 mM Citric Acid Buffer, pH 4.5 with 0.5% SDS	900	10, 15, 20, 30 and 45	2021/08/19
Selpercatinib	Tablet	II (Paddle)	75	0.1 N HCl	900	5, 10, 15, 20 and 30	2026/01/28
Selpercatinib	Capsule	II (Paddle)	75	0.1N HCl	900	5, 10, 15, 20 and 30	2022/07/07
Selumetinib	Capsule	II (Paddle) with sinker	75	Sodium Phosphate Buffer, pH 6.5, with 0.5% Polysorbate 80	1000	10, 20, 30, 45 and 60	2022/07/07
Semaglutide	Tablet	II (Paddle)	70	50 mM Phosphate Buffer with 0.05% Brij 35 (polyoxyethylene lauryl ether), pH 6.8	500	10, 15, 20, 30, 45, 60 and 75	2021/08/19
Semaglutide (1.5 mg, 4 mg, 9 mg, and 25 mg)	Tablet	I (Basket)	75	50 mM Potassium Phosphate Buffer, pH 6.8, 10 mM Sodium Thiosulphate with 0.05% Brij 35	500	3, 5, 10, 12, 15 and 20	2026/03/25
Sephience	Powder	II (Paddle)	75	Phosphate Buffer, pH 6.8	900	5, 10, 15, 20, 30, 45 and 60	2026/03/25
Sertraline HCl	Capsule	II (Paddle) with sinker	75	0.1 N HCl	900	10, 15, 20, 30 and 45	2023/07/07
Sertraline HCl	Tablet	II (Paddle)	75	0.05 M Sodium Acetate Buffer, pH 4.5	900	10, 20, 30 and 45	2004/02/20
Sevabertinib	Tablet	II (Paddle)	50	Phsophate Buffer, pH 6.8 with 0.3% SDS	900	5, 10, 15, 20, 30, 45 and 60	2026/03/25
Sevelamer Carbonate	Tablet			Disintegration Testing in 0.1 N HCl as per USP <701>			2008/10/06
Sevelamer HCl	Capsule			Disintegration Testing in 0.1 N HCl as per USP <701>			2008/04/09
Sevelamer HCl	Tablet			Disintegration Testing in 0.1 N HCl as per USP <701>			2008/04/09
Sibutramine HCl	Capsule	II (Paddle)	50	0.05 M Acetate Buffer, pH 4.0	500	10, 20, 30, 45 and 60	2004/02/25
Sildenafil Citrate	Tablet	I (Basket)	100	0.01 N HCl	900	5, 10, 15 and 30	2006/03/04
Sildenafil Citrate	Film	V (Paddle over Disk)	50	McIvaine Buffer, pH 5.0	900	5, 10, 15, 20, 30, 45 and 60	2026/03/25
Sildenafil Citrate	Suspension	II (Paddle)	50	McIlvaine Buffer, pH 5.0	500	5, 10, 15, 20 and 30	2015/05/28
Silodosin	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Simeprevir Sodium	Capsule	II (Paddle)	75	0.05 M Phosphate Buffer, pH 6.8 with 1.0% polysorbate 20	900	10, 15, 20, 30 and 45	2015/05/28
Simvastatin	Tablet			Refer to USP			2007/06/18