美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Rabeprazole Sodium	Capsule (Delayed Release)	II (Paddle)	Acid Stage: 75 rpm; Buffer Stage: 60 rpm	Acid Stage:0.1 N HCl; Buffer Stage: 0.05 M Phosphate Buffer, pH 6.8 (After Acid Stage, add 250 mL of 0.2 mol/L trisodium phosphate solution).	Acid Stage: 750; Buffer Stage:1000	Acid Stage: 120; Buffer Stage: 10, 15, 20, 25, 30 and 45	2014/05/15
Raloxifene HCl	Tablet			Develop a dissolution method			2023/09/15
Raltegravir Potassium	Tablet (Chewable)			Develop a dissolution method			2023/09/15
Raltegravir Potassium	Tablet			Develop a dissolution method			2023/09/15
Ramelteon	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Ramipril	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Ramipril	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Ranitidine HCl	Tablet			Develop a dissolution method			2024/01/03
Ranitidine HCl	Capsule			Develop a dissolution method			2023/09/15
Ranitidine HCl	Tablet (Effervescent)			Develop a dissolution method			2010/04/08
Ranolazine	Granules (Extended Release)	II (Paddle)	50	0.1 N HCl	900	0.5, 1, 2, 3, 4, 6 and 8 hours	2022/07/07
Ranolazine	Tablet (Extended Release)			Develop a dissolution method			2019/02/07
Rasagiline Mesylate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Regorafenib	Tablet	II (Paddle)	75	Acetate Buffer pH 4.5 with 0.1% Sodium Dodecyl Sulfate (SDS)	900	10, 15, 20, 30 and 45	2015/06/25
Relugolix	Tablet	II (Paddle)	50	50 mM Citrate Buffer, pH 5.5	900	5, 10, 15, 20 and 30	2022/07/07
Repaglinide	Tablet			Refer to USP			2007/07/25
Repotrectinib	Capsule	II (Paddle) with sinker	75	50 mM Sodium Phosphate Buffer, pH 6.8, w/ 0.075% SLS	900	5, 10, 15, 30, 45, 60 and 75	2025/06/23
Resmetirom	Tablet			Develop a dissolution method			2024/09/03
Revumenib Citrate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2026/01/28
Ribavirin	Tablet			Develop a dissolution method			2023/09/15