美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Ranitidine HCl	Capsule			Develop a dissolution method			2023/09/15
Ranolazine	Granules (Extended Release)	II (Paddle)	50	0.1 N HCl	900	0.5, 1, 2, 3, 4, 6 and 8 hours	2022/07/07
Ranolazine	Tablet (Extended Release)			Develop a dissolution method			2019/02/07
Rasagiline Mesylate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Regorafenib	Tablet	II (Paddle)	75	Acetate Buffer pH 4.5 with 0.1% Sodium Dodecyl Sulfate (SDS)	900	10, 15, 20, 30 and 45	2015/06/25
Relugolix	Tablet	II (Paddle)	50	50 mM Citrate Buffer, pH 5.5	900	5, 10, 15, 20 and 30	2022/07/07
Repaglinide	Tablet			Refer to USP			2007/07/25
Repotrectinib	Capsule	II (Paddle) with sinker	75	50 mM Sodium Phosphate Buffer, pH 6.8, w/ 0.075% SLS	900	5, 10, 15, 30, 45, 60 and 75	2025/06/23
Resmetirom	Tablet			Develop a dissolution method			2024/09/03
Ribavirin	Tablet			Develop a dissolution method			2023/09/15
Ribavirin	Capsule			Develop a dissolution method			2023/09/15
Ribociclib	Tablet	II (Paddle)	50	0.01N HCl (degassed)	900	10, 20, 30, 45 and 60	2022/05/12
Rifabutin	Capsule			Refer to USP			2009/12/15
Rifampin	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Rifamycin Sodium	Tablet (Delayed Release)	II (Paddle)	100	Acid stage: HCl 0.1 N with 0.5% w/v Macrogol Cetostearyl Ether; Buffer stage: pH 7.2 Sodium Phosphate buffer		Acid Stage: 2 hours; Buffer Stage: 1, 2, 3 and 4 hours	2021/04/22
Rifapentine	Tablet	II (Paddle)	50	0.8% SLS in Phosphate Buffer, pH 7.0	900	10, 20, 30, 45, 60 and 90	2004/02/25
Rifaximin (200 mg)	Tablet	II (Paddle)	75	0.1M sodium phosphate buffer pH 7.4 containing 0.45% Sodium Lauryl Sulfate	1000	10, 20, 30, 45, 60, 90 and 120	2011/07/21
Rifaximin (550 mg)	Tablet	II (Paddle)	75	0.1M sodium phosphate buffer pH 7.4 containing 0.8% Sodium Lauryl Sulfate	1000	10, 20, 30, 45, 60, 90 and 120	2011/07/21
Rilpivirine HCl	Tablet	II (Paddle)	75	0.5% Polysorbate 20 in 0.01N HCl (pH=2.0)	900	10, 20, 30, 45 and 60	2013/08/15
Riluzole	Tablet	II (Paddle)	50	0.1 N HCl	900	10, 20, 30, 45 and 60	2004/02/18