美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Prednisone	Tablet (Delayed Release)			Develop a dissolution method			2023/09/15
Prednisone	Tablet			Develop a dissolution method			2024/01/03
Pregabalin	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Pregabalin	Tablet (Extended Release)	II (Paddle)	50	0.06 M HCl	900	1, 2, 4, 6, 8, 10, 12, 16 and 24 hours	2018/02/08
Pretomanid	Tablet	II (Paddle)	75	0.1 N HCl with 0.5% hexadecyltrimethylammonium (HDTMA)	1000	5, 10, 15, 20, 30 and 45	2021/04/22
Primaquine Phosphate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Primidone	Tablet			Develop a dissolution method			2023/11/30
Probenecid; Sulopenem Etzadroxil	Tablet	II (Paddle)	75	0.05 M Phosphate Buffer, pH 6.8	900	5, 10, 15, 20, 30, 45 and 60	2026/01/28
Procarbazine HCl	Capsules			Develop a dissolution method			2023/09/15
Prochlorperazine	Rectal Suppository	I (Suppository, dissolution baskets, palmieri type)	100	0.1 N HCl at 38° C	900	10, 20, 30 and 45	2006/08/17
Prochlorperazine Maleate	Tablet	II (Paddle)	75	0.1 N HCl	500	10, 20, 30, 45, 60, 75, and 90	2021/04/22
Progesterone	Capsule			Develop a quantitative rupture test			2010/04/08
Progesterone	Vaginal Insert	II (Paddle)	50	0.25% sodium dodecyl sulfate (SDS) in DI water	900	5, 10, 15, 20 and 30	2012/10/04
Progesterone	Gel	I (Basket) with Diacell sample holder	100	Methanol:water 20:80	1000	2, 4, 8, 12, 20, 24, 48 and 72 hours	2023/03/30
Promethazine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Promethazine HCl	Rectal Suppository			Develop a method to characterize in vitro release			2016/10/20
Propafenone HCl	Capsule (Extended Release)			Refer to USP			2017/11/02
Propafenone HCl	Tablet			Refer to USP			2017/11/02
Propranolol HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2021/04/22
Propranolol HCl	Capsule (Extended Release)			Refer to USP			2007/07/25