FDA药品溶出方法数据库
(FDA-Recommended Dissolution Methods Database)
药品通用名称 剂型 USP溶出装置 速度 溶出介质 介质体积 建议取样时间(分钟) 更新日期
Hydrochlorothiazide/Valsartan Tablet Refer to USP 2016/07/28
Hydrochlorothizide/Triamterene Capsule Refer to USP 2008/10/06
Hydrocodone Bitartrate Capsule (Extended Release) I (Basket) 100 0.05 M Phosphate Buffer, pH 6.8 500 1, 2, 4, 6, 8, 10 and 12 hours 2015/05/28
Hydrocodone Bitartrate Tablet (Extended Release) I (Basket-10 mesh) 100 Simulated gastric fluid (SGF) without enzyme (pH 1.2) 900 1, 2, 4, 8, 12, 16, 20 and 24 hours 2016/04/14
Hydrocodone Bitartrate/Ibuprofen Tablet II (Paddle) 50 Phosphate Buffer, pH 7.2 900 5, 10, 15 and 30 2004/02/04
Hydrocortisone Tablet Develop a dissolution method 2024/01/03
Hydromorphone HCl Tablet (Extended Release) Develop a dissolution method 2023/09/15
Hydromorphone HCl Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Hydroxychloroquine Sulfate Tablet Refer to FDA's Dissolution Guidance, 2018 2020/04/16
Hydroxyurea Capsule Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Hydroxyurea Tablet Refer to FDA's Dissolution Guidance, 2018 2022/07/07
Hydroxyzine HCl Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Hydroxyzine Pamoate Capsule Refer to USP 2009/04/02
Hydroxyzine Pamoate Suspension Develop a dissolution method 2009/04/02
Ibandronate Sodium Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Ibrexafungerp Citrate Tablet II (Paddle) 50 0.1N HCl 900 10, 15, 20, 30 and 45 2023/02/09
Ibrutinib Capsule II (Paddle) 75 3.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 5, 10, 20, 30 and 45 2015/06/25
Ibrutinib Suspension II (Paddle) 25 0.05 M potassium phosphate buffer, pH 6.8, w/ 1.5% (w/v) Tween 20 900 5, 10, 15, 20, 30, 45 and 60 2025/09/08
Ibrutinib (140 and 280 mg) Tablet II (Paddle) 75 3.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 10, 20, 30, 45 and 60 2020/04/02
Ibrutinib (420 and 560 mg) Tablet II (Paddle) 75 6.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 10, 20, 30, 45 and 60 2020/04/02

数据库说明:

当前数据更新日期:2025年12月17日。
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