美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Guaifenesin	Tablet (Extended Release)	I (Basket)	75	0.1 N HCl	900	1, 2, 4, 6 and 12 hours	2007/01/03
Guaifenesin/Pseudoephedrine Hydrochloride	Tablet (Extended Release)	I (Basket)	50	0.01 N HCl	900	1, 2, 6, and 12 hours	2008/11/25
Guanfacine	Tablet (Extended Release)	II (Paddle)	75	HCl Buffer, pH 2.2	900	1, 2, 4, 6, 8, 10, 12, 16, 20 and 24 hours	2010/07/01
Guanfacine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018	500		2021/08/19
Haloperidol	Tablet			Refer to USP			2008/11/25
Homatropine Methylbromide/Hydrocodone Bitartrate	Tablet			Develop a dissolution method			2024/01/03
Hydralazine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Hydrochlorothiazide	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Hydrochlorothiazide	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Hydrochlorothiazide/Irbesartan	Tablet	II (Paddle)	50	0.1 N HCl	1000	10, 20, 30 and 45	2008/09/24
Hydrochlorothiazide/Lisinopril	Tablet	II (Paddle)	50	0.1 N HCl	900	10, 20, 30, 45 and 60	2004/02/03
Hydrochlorothiazide/Losartan Potassium	Tablet			Develop a dissolution method			2023/09/15
Hydrochlorothiazide/Metoprolol Succinate	Tablet (Extended Release)	II (Paddle)	Hydrochlorothiazide: 100; Metoprolol succinate: 75	Hydrochlorothiazide: 0.1N HCl; Metoprolol succinate: Phosphate Buffer, pH 6.8	Hydrochlorothiazide: 500; Metoprolol succinate: 500	Hydrochlorothiazide: 10, 15, 20, 30, and 45 minutes; Metoprolol succinate: 1, 2, 4, 6, 8, 12, 16, 20 and 24 hours	2013/10/31
Hydrochlorothiazide/Metoprolol Tartrate	Tablet			Refer to USP			2012/01/05
Hydrochlorothiazide/Moexipril HCl	Tablet	II (Paddle)	50	0.1 N HCl	900	5, 10, 15 and 30	2004/02/10
Hydrochlorothiazide/Olmesartan Medoxomil	Tablet	II (Paddle)	50	0.05 M Phosphate Buffer, pH 6.8	900	5, 10, 15, 20, 30, 45 and 60	2007/07/09
Hydrochlorothiazide/Quinapril HCl	Tablet			Develop a dissolution method			2023/09/15
Hydrochlorothiazide/Spironolactone	Tablet			Refer to USP			2009/08/27
Hydrochlorothiazide/Telmisartan	Tablet			Refer to USP			2016/06/30
Hydrochlorothiazide/Triamterene	Tablet			Refer to USP			2013/07/31