美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Ibuprofen	Tablet (Chewable)	II (Paddle)	50	0.05 M Phosphate Buffer, pH 7.2	900	10, 20, 30 and 45	2004/02/04
Ibuprofen	Capsule (Soft-Gelatin/Liquid Fill)	I (Basket)	150	50mM Phosphate Buffer, pH 7.2	900	5, 10, 20, 30 and 45	2013/05/09
Ibuprofen	Tablet			Refer to USP			2007/07/25
Ibuprofen	Suspension			Refer to USP			2008/11/04
Ibuprofen	Suspension/Drop	II (Paddle)	50	Phosphate Buffer, pH 7.2	900	5, 10, 15 and 20	2008/11/04
Ibuprofen Potassium	Capsule (Soft-Gelatin/Liquid Fill)	I (Basket)	150	Phosphate Buffer, pH 7.2	900	5, 10, 20 and 30	2004/02/04
Ibuprofen Sodium	Capsule	I (Basket)	150	Phosphate Buffer, pH 7.2	900	5, 10, 15, 20 and 30	2015/06/25
Ibuprofen/Diphenhydramine	Capsule	I (Basket)	100	Phosphate Buffer (200 mM), pH7.2	900	10, 20, 30 and 45	2007/01/03
Ibuprofen/Oxycodone HCl	Tablet	I (Basket)	100	Phosphate buffer, pH 7.2	500	10, 20, 30 and 45	2007/04/09
Ibuprofen/Phenylephrine HCl	Tablet	II (Paddle)	50	50 mM Potassium Phosphate Buffer, pH 6.5, (degassed)	900	10, 15, 20, 30 and 45	2012/01/05
Ibuprofen/Pseudoephedrine HCl	Capsule	I (Basket)	150	Tier 1: 0.05 M phosphate buffer, pH 7.2 Tier 2: 0.05 M phosphate buffer, pH 7.2 with NMT 1750 USP protease units/L of 1 X USP pancreatin	900	10, 20, 30 and 45	2006/03/04
Ibuprofen/Pseudoephedrine HCl	Suspension	II (Paddle)	50	0.05 M Phosphate Buffer, pH 7.2	900	5, 10, 15 and 30	2004/02/04
Idelalisib	Tablet	II (Paddle)	75	0.01 N HCl	750	5, 10, 15, 20 and 30	2015/08/27
Iloperidone	Tablet	II (Paddle)	50	0.1 N HCl	500	5, 10, 15, 30, 45 and 60	2010/08/05
Imatinib Mesylate	Tablet	II (Paddle)	50	0.1 N HCl	1000	5, 10, 15, 20 and 30	2011/09/22
Imipramine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Imipramine Pamoate	Capsule	I (Basket)	100	0.1 N HCl without pepsin and with 0.3% pepsin (addition of pepsin is recommended only when significant slow dissolution is observed)	900	30, 60, 90, 120, 150 and 180	2008/01/14
Indapamide	Tablet			Refer to USP			2008/04/15
Indinavir Sulfate	Capsule	II (Paddle)	50	0.1 M Citrate Buffer, pH 3.8	900	10, 15, 20 and 30	2004/02/04
Indomethacin	Rectal Suppository			Refer to USP			2021/08/26