美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Enzalutamide	Capsule	II (Paddle) with sinker	50	Tier 1 Medium: 0.3% cetyl trimethyl ammonium bromide (CTAB) in 0.1 N HCl;Tier 2 Medium: 0.3% CTAB in 0.1 N HCl containing Pepsin 600,000 USP units/L.	900	10, 15, 20, 30 and 45	2015/05/28
Eplerenone	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Eprosartan Mesylate	Tablet	II (Paddle)	75	0.2 M Phosphate Buffer, pH 7.5	1000	15, 30, 45 and 60	2008/07/14
Eprosartan Mesylate/Hydrochlorothiazide	Tablet	II (Paddle)	75	0.2 M Phosphate Buffer, pH 7.5	1000	10, 20, 30 and 45	2008/02/19
Erdafitinib	Tablet	I (Basket)	75	0.01 N HCl, pH 2	500	5, 10, 15, 20, 30, 45 and 60
Ergocalciferol	Capsule	II (Paddle)	100	0.5 N NaOH with 10% Triton-X-100	500	15, 30, 45, 60 and 90	2010/08/05
Erlotinib HCl	Tablet	II (Paddle)	75	0.02% Tween 80 in 0.01 N HCl	1000	5, 10, 15, 20, 30 and 45	2018/10/18
Ertugliflozin	Tablet			Refer to FDA's Dissolution Guidance, 2018			2025/06/23
Erythromycin	Tablet			Refer to USP			2015/12/24
Erythromycin	Tablet (Delayed Release)			Refer to USP			2013/10/31
Erythromycin Ethylsuccinate	Suspension	II (Paddle)	75	Monobasic Sodium Phosphate, pH 6.8 Buffer with 1% SLS Buffer w/ 1% SLS	900	10, 20, 30, 45 and 60	2004/01/27
Erythromycin Ethylsuccinate	Oral granule			Develop a dissolution method			2016/06/30
Erythromycin Ethylsuccinate	Tablet			Refer to USP			2021/04/22
Erythromycin Ethylsuccinate/Sulfisoxazole Acetyl	Granules for Oral Suspension			Develop a dissolution method			2010/09/02
Escitalopram Oxalate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Escitalopram Oxalate	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Eslicarbazepine Acetate	Tablet	II (Paddle)	100	Acetate Buffer, pH 4.5	1000	5, 10, 15, 20, 30 and 45	2015/08/27
Esomeprazole Magnesium	Capsule (Delayed Release Pellets)			Refer to USP			2015/08/27
Esomeprazole Magnesium	For Oral Suspension (Delayed Release)	II (Paddle	100	Acid stage: 0.1 N HCl; Buffer stage: Sodium Phosphate Buffer, pH 6.8	Acid stage: 300; Buffer stage: 1000	Acid stage: 120; Buffer stage: 10, 20, 30, 45 and 60	2010/09/02
Esomeprazole Magnesium	Tablet (Orally Disintegrating, Delayed Release)	II (Paddle)	Acid stage: 100; Buffer stage: 75	Acid stage: 0.1 N HCl; Buffer stage: Phosphate Buffer, pH 6.8	Acid stage: 300; Buffer stage: 1000	Acid stage: 120; Buffer stage: 5, 10, 20, 30 and 45	2021/04/22