美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Emtricitabine/Rilpivirine HCl/Tenofovir Alafenamide Fumarate	Tablet	II (Paddle	75	Rilpivirine (RPV): 0.5% Polysorbate 20 in 0.01 N HCl; Emtricitabine (ETC) and Tenofovir alafenamide (TAF): 50 mM Sodium Citrate, pH 5.5,	RPV: 1000 mL; ETC and TAF: 500 mL	5, 10, 15, 20, 30 and 45	2016/07/28
Emtricitabine/Rilpivirine HCl/Tenofovir Disoproxil Fumarate	Tablet	II (Paddle) with sinker	75	0.5%(w/w) polysorbate 20 in 0.01N HCl (pH 2.0)	1000	Emtricitabine and Tenofovir: 5, 10, 15, 20 and 30; Rilpivirine: 10, 20, 30, 45, 60, 75, 90 and 120	2015/01/15
Emtricitabine/Tenofovir Alafenamide Fumarate	Tablet	II (Paddle	75	50 mM Sodium Citrate buffer, pH 5.5	500	5, 10, 15, 20, 30 and 45	2016/07/28
Emtricitabine/Tenofovir Disoproxil Fumarate	Tablet	II (Paddle)	50	0.01 N HCl	900	5, 10, 15, 30 and 45	2007/01/03
Enalapril Maleate	Tablet			Refer to USP			2008/09/03
Encorafenib	Capsule	II (Paddle) with sinker	100	Ammonium acetate buffer, pH 4.5	900	15, 30, 45 and 60	2025/03/17
Ensartinib Hydrochloride	Capsule	II (Paddle) with sinker	50	0.1 N HCl	900	15, 20, 30, 45 and 60	2026/01/28
Entacapone	Tablet	II (Paddle)	50	Phosphate Buffer, pH 5.5	900	10, 20, 30 and 45	2004/01/29
Entecavir	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Entrectinib	Capsule	II (Paddle) with Sinker	75	50 mM Potassium Phosphate, pH 6.0 with 0.374% w/v polysorbate 80	1000	15, 20, 30, 45, 60 and 75	2021/08/19
Enzalutamide	Tablet	II (Paddle)	50	Phosphate Buffer, pH 7.5	900	5, 10, 15, 20, 30 and 45	2022/05/12
Enzalutamide	Capsule	II (Paddle) with sinker	50	Tier 1 Medium: 0.3% cetyl trimethyl ammonium bromide (CTAB) in 0.1 N HCl;Tier 2 Medium: 0.3% CTAB in 0.1 N HCl containing Pepsin 600,000 USP units/L.	900	10, 15, 20, 30 and 45	2015/05/28
Eplerenone	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Eprosartan Mesylate	Tablet	II (Paddle)	75	0.2 M Phosphate Buffer, pH 7.5	1000	15, 30, 45 and 60	2008/07/14
Eprosartan Mesylate/Hydrochlorothiazide	Tablet	II (Paddle)	75	0.2 M Phosphate Buffer, pH 7.5	1000	10, 20, 30 and 45	2008/02/19
Erdafitinib	Tablet	I (Basket)	75	0.01 N HCl, pH 2	500	5, 10, 15, 20, 30, 45 and 60
Ergocalciferol	Capsule	II (Paddle)	100	0.5 N NaOH with 10% Triton-X-100	500	15, 30, 45, 60 and 90	2010/08/05
Erlotinib HCl	Tablet	II (Paddle)	75	0.02% Tween 80 in 0.01 N HCl	1000	5, 10, 15, 20, 30 and 45	2018/10/18
Ertugliflozin	Tablet			Refer to FDA's Dissolution Guidance, 2018			2025/06/23
Erythromycin	Tablet			Refer to USP			2015/12/24