FDA药品溶出方法数据库
(FDA-Recommended Dissolution Methods Database)
药品通用名称 剂型 USP溶出装置 速度 溶出介质 介质体积 建议取样时间(分钟) 更新日期
Dextromethorphan Polistirex Suspension (Extended Release) II (Paddle) 50 0.1 N HCl 500 30, 60, 90 and 180 2008/10/06
Diazepam Film Develop a dissolution method 2025/06/23
Diazepam Tablet Refer to USP 2007/07/25
Diazoxide Oral suspension Develop a dissolution method 2014/02/14
Diclofenac Capsule I (Basket) 100 10 mM Citrate Buffer pH 5.5 with 0.05% Sodium Dodecyl Sulfate (SDS) 900 5, 10, 20, 30 and 45 2015/06/25
Diclofenac Epolamine Topical patch V (Paddle over Disk) with a watchdish (a diameter of 6 cm) 50 pH 6.8 phosphate buffer at 32 ± 0.5°C 500 15, 30, 45, 60, 90, 120 and 180 2010/10/21
Diclofenac Potassium Powder for Oral Solution II (Paddle 75 0.05M phosphate buffer (TriSodium Phosphate Dodecahydrate in 0.1 N HCl and pH adjusted to 6.8) 400 2.5, 5, 7.5 and 10 2010/10/21
Diclofenac Potassium Capsule II (Paddle 50 50 mM Phosphate buffer pH 6.8 900 10, 15, 20, 30 and 45 2010/10/21
Diclofenac Potassium Tablet II (Paddle) 50 SIF without enzyme 900 10, 20, 30, 45, 60 and 90 2004/01/27
Diclofenac Sodium Tablet (Extended Release) Refer to USP 2009/06/10
Diclofenac Sodium Tablet (Delayed Release) Refer to USP 2009/06/10
Diclofenac Sodium/Misoprostol Enteric Coated Tablet (Delayed Release) II (Paddle) (diclo) 100 (diclo) Diclofenac: Acid Stage: 0.1 N HCl Buffer Stage: 750ml 0.1N HCL+250ml 0.2M phos.buffer, pH 6.8 (Method A) Misoprostol: Develop a dissolution method Diclo: Acid: 750 Buffer:1000 Diclo.: 120 (acid) 15, 30, 45 and 60 (Buffer) 2023/09/15
Dicloxacillin Sodium Capsule Develop a dissolution method 2024/01/03
Dicyclomine Hydrochloride Tablet Refer to USP 2022/05/12
Didanosine Tablet (Chewable) Develop a dissolution method 2023/09/15
Didanosine Capsule (Delayed Release Pellets) I (Basket) 100 Acid stage: 0.1 N HCl; Buffer stage: 0.1 N HCl:0.2M Tribasic Sodium Phosphate (3:1), pH 6.8 1000 Acid stage: 60, 90 and 120; Buffer stage: 10, 20, 30, 45 and 60 2004/01/26
Dienogest/Estradiol Valerate Tablet Develop a dissolution method 2023/09/15
Diethylpropion HCl Tablet (Extended Release) Develop a dissolution method 2023/09/15
Diflunisal Tablet Refer to USP 2008/04/15
Digoxin Tablet Refer to USP 2007/06/18

数据库说明:

当前数据更新日期:2026年02月07日。
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