美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Deferasirox	Granule	II (Paddle)	75	Phosphate Buffer, pH 6.8 with 0.5% Tween 20	900	5, 10, 15, 20 and 30	2017/11/02
Deferiprone	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Deferiprone (1 GM)	Tablet	I (Basket)	100	Acidic Stage: 0.1 N HCl, Buffer Stage: 0.05 M Phosphate buffer, pH 6.8.		Acid Stage: 2 hours; Buffer Stage: 1, 2, 3 and 4 hours	2022/07/07
Deflazacort	Suspension	II (Paddle)	25	Simulated Gastric Fluid, pH 1.2	500	5, 10, 15 and 30	2023/07/07
Deflazacort	Tablet	II (Paddle)	50	50 mM Phosphate buffer w/0.3% SLS, pH 6.8	500	5, ,15, 30 and 45	2023/07/07
Degarelix Acetate	Powder for Injection			Develop a method to characterize in vitro release			2023/10/06
Delafloxacin Meglumine	Tablet	II (Paddle)	60	0.05 M Phosphate Buffer, pH 7.4 (degassed)	900	5, 10, 15, 20 and 30	2017/11/16
Delavirdine Mesylate	Tablet	II (Paddle)	50	0.05 M Phosphate Buffer, pH 6.0 containing 0.6% w/v SDS	900	10, 20, 30, 45 and 60	2007/12/03
Demeclocycline HCl	Capsule			Develop a dissolution method			2024/01/03
Demeclocycline HCl	Tablet			Develop a dissolution method			2024/01/03
Desipramine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Desloratadine	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Desloratadine	Tablet (Orally Disintegrating)	II (Paddle)	50	0.1 N HCl	900	3, 6, 10, 15	2007/06/18
Desloratadine/Pseudoephedrine Sulfate (2.5 mg/120 mg)	Tablet (Extended Release)	II (Paddle)	50	First hour: 0.1 N HCl; After 1 hour: 0.1M Potassium Phosphate Buffer pH 7.5	1000	For Desloratadine: 10, 20, 30 and 45; For Pseudoephedrine Sulfate: 1, 2, 6 and 8 hours	2009/04/02
Desloratadine/Pseudoephedrine Sulfate (5 mg/240 mg)	Tablet (Extended Release)	II (Paddle)	50	First hour: 0.1 N HCl; After 1 hour: 0.1M Potassium Phosphate Buffer pH 7.5	1000	For Desloratadine: 10, 20, 30 and 45; For Pseudoephedrine Sulfate: 1, 2, 4, 8, 16 and 24 hours	2009/04/02
Desmopressin Acetate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Desogestrel/Ethinyl Estradiol	Tablet			Refer to USP			2008/11/04
Desvenlafaxine Succinate	Tablet (Extended Release)			Develop a dissolution method			2023/09/15
Deucravacitinib	Tablet	II (Paddle)	75	50 mM potassium phosphate buffer, pH 6.3 with 0.01% (w/v) Brij®35	1000	10, 20, 30, 45 and 60	2023/11/30
Deuruxoutinib Phosphate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2026/01/28