美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Clevidipine	Emulsion			Develop a dissolution method			2025/09/08
Clindamycin HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Clindamycin Phosphate	Suppository			Develop a method to characterize in vitro release			2026/03/25
Clobazam	Film	V (Paddle over Disk), with 56 mm, 40 mesh stainless steel disk.	75	0.1 N HCl	900	2, 5, 10, 15, 20 and 30	2021/04/22
Clobazam	Tablet	II (Paddle)	75	0.1 N HCl (degassed)	900	5, 10, 20, 30, 45 and 60	2013/07/31
Clobazam	Oral Suspension	II (Paddle)	75	0.1 N HCl (degassed)	900	5, 10, 15, 20, 25 and 30	2013/07/31
Clomiphene Citrate	Tablet			Develop a dissolution method			2024/01/03
Clomipramine HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Clonazepam	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Clonazepam	Suspension			Develop a dissolution method			2024/11/01
Clonazepam	Tablet (Orally Disintegrating)			Develop a dissolution method			2023/09/15
Clonidine	Transdermal			Refer to USP			2009/02/18
Clonidine ( 0.1 mg)	Tablet (Extended Release)	II (Paddle) with sinker	50	Acid stage: 0.01 N HCl; Buffer stage: Phosphate Buffer, pH 7.0	Acid stage: 500; Buffer stage: 500	Acid stage: 1 and 2 hours; Buffer stage: 1, 2, 4, 6, 10, 14 and 16 hours	2012/01/26
Clonidine ( EQ. 0.17 mg and EQ. 0.26 mg)	Tablet (Extended Release)	II (Paddle)	50	500 mL 0.1N HCl for the 1st hour, then add 400 mL 0.27M Sodium Phosphate (Dibasic) buffer solution	Acid stage: 500; Buffer stage: 900	1, 2, 3, 6, 9, 12, 16, 20 and 24 hours	2010/07/01
Clonidine HCl	Tablet			Refer to USP			2007/06/18
Clonidine HCl (0.1 mg & 0.2 mg)	Tablet (Extended Release)	II (Paddle) with sinker	50	Acid stage: 0.01 N HCl; Buffer stage: Phosphate Buffer, pH 7.0	Acid stage: 500; Buffer stage: 500	Acid stage: 1 and 2 hours; Buffer stage: 1, 2, 4, 6, 10, 14 and 16 hours	2015/08/27
Clonidine Hydrochloride	Suspension, Extended Release	II (Paddle)	50	0.6 M KH2PO4 solution, pH 4.3	900	0.5, 1, 2, 3, 4, 6, 8, 12, 14, 16, 18 and 24 hours	2025/06/23
Clopidogrel Bisulfate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Clorazepate Dipotassium	Tablet			Refer to USP			2013/01/31
Clotrimazole	Tablet (Vaginal)	II (Paddle)	50	0.1 N HCl	900	10, 20, 30 and 45	2004/01/24