FDA药品溶出方法数据库
(FDA-Recommended Dissolution Methods Database)
药品通用名称 剂型 USP溶出装置 速度 溶出介质 介质体积 建议取样时间(分钟) 更新日期
Ciprofloxacin/Ciprofloxacin HCl (AB) Tablet (Extended Release) II (Paddle) 50 0.1 N HCl 900 15, 30, 60, and 120 2008/01/14
Ciprofloxacin/Dexamethasone Otic Suspension Develop a method to characterize in vitro release 2016/03/17
Citalopram Capsule Refer to FDA's Dissolution Guidance, 2018 2023/07/07
Citalopram HBr Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Citalopram Hydrobromide Capsule II (Paddle) 50 0.1 N HCl 900 10, 20, 30 and 45 2008/10/06
Cladribine Tablet II (Paddle) 50 Phosphate Buffer, pH 6.8  (deaerated) 900 5, 10, 15, 20 and 30 2022/05/12
Clarithromycin Tablet (Extended Release) Refer to USP 2008/10/06
Clarithromycin Suspension II (Paddle) 50 0.05 M Phosphate Buffer, pH 6.8 900 10, 20, 30, 45 and 60 2004/01/23
Clarithromycin Tablet Refer to USP 2007/07/25
Clevidipine Emulsion Develop a dissolution method 2025/09/08
Clindamycin HCl Capsule Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Clobazam Tablet II (Paddle) 75 0.1 N HCl (degassed) 900 5, 10, 20, 30, 45 and 60 2013/07/31
Clobazam Oral Suspension II (Paddle) 75 0.1 N HCl (degassed) 900 5, 10, 15, 20, 25 and 30 2013/07/31
Clobazam Film V (Paddle over Disk), with 56 mm, 40 mesh stainless steel disk. 75 0.1 N HCl 900 2, 5, 10, 15, 20 and 30 2021/04/22
Clomiphene Citrate Tablet Develop a dissolution method 2024/01/03
Clomipramine HCl Capsule Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Clonazepam Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Clonazepam Suspension Develop a dissolution method 2024/11/01
Clonazepam Tablet (Orally Disintegrating) Develop a dissolution method 2023/09/15
Clonidine Transdermal Refer to USP 2009/02/18

数据库说明:

当前数据更新日期:2025年12月11日。
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