美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Carbidopa/Levodopa	Tablet			Refer to FDA's Dissolution Guidance, 2018			2021/04/22
Carbidopa/Levodopa	Capsule (Extended Release)	I (Basket)	75	Acid stage: Simulated Gastric Fluid [SGF] without enzyme; Buffer stage: pH 7.0, 50 mM Phosphate Buffer	Acid stage: 500 mL [for 23.75/95 mg strength], 900 mL [other strengths]; Buffer stage:500 mL [for 23.75/95 mg strength], 900 mL [other strengths]	Acid stage: 30, 60 and 120; Buffer stage: 15, 30, 60, 90, 120, 180 and 240	2016/04/07
Carbinoxamine Maleate	Suspension (Extended Release)	II (Paddle)	50	0.4 M Phosphate Buffer	900 [ 895 mL 0.4 M Buffer +5 mL Suspension]	0.5, 1, 2, 3, 4, 6, 8 and 12 hours	2016/06/02
Carbinoxamine Maleate	Tablet			Develop a dissolution method			2024/01/03
Carglumic Acid	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Cariprazine HCl	Capsule	I (Basket)	100	Sodium Acetate Buffer, pH 5.0 (degas)	500	5, 10, 15, 20, 30 and 45	2016/06/30
Carisoprodol	Tablet			Refer to USP			2010/01/29
Carvedilol	Tablet			Refer to USP			2015/12/24
Carvedilol	Tablet	II (Paddle)	50	SGF without enzyme	900	10, 20, 30 and 45	2004/01/21
Carvedilol Phosphate	Capsule (Extended Release)	II (Paddle)	100	0.1 N HCl	900	1, 2, 4, 6, 8, 12, 18 and 24 hours	2013/10/31
Cedazuridine/Decitabine	Tablet	II (Paddle)	75	50 mM phosphate buffer, pH 6.8	900	5, 10, 15 and 30	2022/07/07
Cefaclor	Tablet (Chewable)			Develop a dissolution method			2024/01/03
Cefaclor	Tablet (Extended Release)			Refer to USP			2011/03/03
Cefaclor	Capsule			Develop a dissolution method			2024/01/03
Cefadroxil	Tablet			Develop a dissolution method			2024/01/03
Cefadroxil	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Cefadroxil	Suspension			Develop a dissolution method			2023/09/15
Cefdinir	Capsule	II (Paddle)	50	Phosphate Buffer, pH 6.8	900	5, 10, 15, 30 and 45	2007/07/25
Cefdinir	Suspension	II (Paddle)	50	0.05 M Phosphate buffer, pH 6.8	900	10, 20, 30 and 45	2007/04/09
Cefditoren Pivoxil	Tablet	II (Paddle)	75	Simulated Gastric Fluid without enzyme	900	5, 10, 15, 20 and 30	2010/01/15