美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Captopril	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Carbamazepine	Tablet (Extended Release)			Develop a dissolution method			2024/01/03
Carbamazepine	Tablet			Develop a dissolution method			2024/01/03
Carbamazepine	Tablet (Chewable)			Develop a dissolution method			2023/09/15
Carbamazepine	Suspension			Develop a dissolution method			2023/09/15
Carbamazepine	Capsule (Extended Release)	II (Paddle)	75	First 4 hours: Dilute Acid, pH 1.1. After 4 hours: Phosphate Buffer, pH 7.5 with 0.1% sodium lauryl sulfate (SLS).	First 4 h: 900. After 4 h: 900	1, 2, 4, 6, 8, 10 and 12 hours	2011/09/01
Carbidopa	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Carbidopa/Entacapone/Levodopa	Tablet	I (Basket)	Carbidopa and Levodopa: 50; Entacapone: 125	For both Carbidopa and Levodopa: 0.1 N HCl, For Entacapone: Phosphate buffer pH 5.5	Carbidopa and Levodopa: 750 ml. Entacapone: 900 ml	10, 20, 30, 45 and 60	2007/01/03
Carbidopa/Levodopa	Suspension (Enteral)	II (Paddle)	25	0.05 M Sodium Acetate Buffer, pH 4.5	500	5, 10, 15, 20, 30, 40 and 60	2016/10/20
Carbidopa/Levodopa	Tablet (Extended Release)	II (Paddle)	50	0.1 N HCl	900	0.5, 0.75, 1, 1.5, 2, 2.5, 3 and 4 hours	2013/08/15
Carbidopa/Levodopa	Tablet			Refer to FDA's Dissolution Guidance, 2018			2021/04/22
Carbidopa/Levodopa	Capsule (Extended Release)	I (Basket)	75	Acid stage: Simulated Gastric Fluid [SGF] without enzyme; Buffer stage: pH 7.0, 50 mM Phosphate Buffer	Acid stage: 500 mL [for 23.75/95 mg strength], 900 mL [other strengths]; Buffer stage:500 mL [for 23.75/95 mg strength], 900 mL [other strengths]	Acid stage: 30, 60 and 120; Buffer stage: 15, 30, 60, 90, 120, 180 and 240	2016/04/07
Carbidopa/Levodopa	Tablet (Orally Disintegrating)	II (Paddle)	50	0.1 N HCl	750	5, 10, 15, 30, and 45	2007/07/25
Carbinoxamine Maleate	Tablet			Develop a dissolution method			2024/01/03
Carbinoxamine Maleate	Suspension (Extended Release)	II (Paddle)	50	0.4 M Phosphate Buffer	900 [ 895 mL 0.4 M Buffer +5 mL Suspension]	0.5, 1, 2, 3, 4, 6, 8 and 12 hours	2016/06/02
Carglumic Acid	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Cariprazine HCl	Capsule	I (Basket)	100	Sodium Acetate Buffer, pH 5.0 (degas)	500	5, 10, 15, 20, 30 and 45	2016/06/30
Carisoprodol	Tablet			Refer to USP			2010/01/29
Carvedilol	Tablet	II (Paddle)	50	SGF without enzyme	900	10, 20, 30 and 45	2004/01/21
Carvedilol	Tablet			Refer to USP			2015/12/24