Structural Formula Vector Image
Title: Tryptophol
CAS Registry Number: 526-55-6
CAS Name: 3-Indoleethanol
Additional Names: 3-w-hydroxyethylindole; 2-(3-indolyl)ethyl alcohol; 2-indolyl(3)-ethanol; b-indolylethyl alcohol; 3-b-hydroxyethylindole
Molecular Formula: C10H11NO
Molecular Weight: 161.20
Percent Composition: C 74.51%, H 6.88%, N 8.69%, O 9.93%
Literature References: Prepd by treatment of indolemagnesium bromide with ethylene oxide: Oddo, Cambieri, Gazz. Chim. Ital. 60, 19 (1939); Snyder, Pilgrim, J. Am. Chem. Soc. 70, 1962 (1948); by Bouveault-Blanc reduction of 3-indoleacetic ester: Jackson, J. Biol. Chem. 88, 659 (1930); by treatment of indolemagnesium iodide with ethylene chlorohydrin: Majima, Hoshino, Ber. 58, 2042 (1925); from gramine: Snyder, Pilgrim, J. Am. Chem. Soc. 70, 3770 (1948). By lithium aluminum hydride reduction of methyl 3-indoleglycolate: Speeter, Anthony, US 3076814 (1963 to Upjohn).
Properties: Platelets from ether + petr ether, mp 59°. bp2.0 174°. Slightly sol in water. Sol in methanol, ethanol, ether, acetone, chloroform, ethyl acetate, glacial acetic acid. Moderately sol in benzene, amyl alcohol, hot carbon disulfide. Sparingly sol in petr ether.
Melting point: mp 59°
Boiling point: bp2.0 174°

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