Structural Formula Vector Image
Title: Talipexole
CAS Registry Number: 101626-70-4
CAS Name: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine
Additional Names: 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine
Molecular Formula: C10H15N3S
Molecular Weight: 209.31
Percent Composition: C 57.38%, H 7.22%, N 20.08%, S 15.32%
Literature References: a2-Adrenoceptor and dopamine D2-receptor agonist. Prepn: G. Griss et al., DE 2040510 (1972 to Thomae); eidem, US 3804849 (1974 to Boehringer, Ing.). Dopaminergic effects: P. A. Johansen et al., Life Sci. 43, 515 (1988); S. K. Kulkarni, K. Chopra, Methods Find. Exp. Clin. Pharmacol. 12, 99 (1990). Clinical evaluation in Parkinson's disease: Y. Mizuno et al., Drug Invest. 5, 186 (1993).
Derivative Type: Dihydrochloride
CAS Registry Number: 36085-73-1
Manufacturers' Codes: B-HT-920
Trademarks: Domin (Boehringer, Ing.)
Molecular Formula: C10H15N3S.2HCl
Molecular Weight: 282.23
Percent Composition: C 42.56%, H 6.07%, N 14.89%, S 11.36%, Cl 25.12%
Properties: mp 245° (dec).
Melting point: mp 245° (dec)
Therap-Cat: Antiparkinsonian.
Keywords: a-Adrenergic Agonist; Antiparkinsonian; Dopamine Receptor Agonist.

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