Dehydrocholic Acid
Structural Formula Vector Image
Title: Dehydrocholic Acid
CAS Registry Number: 81-23-2
CAS Name: (5b)-3,7,12-Trioxocholan-24-oic acid
Additional Names: 3,7,12-triketocholanic acid
Trademarks: Acolen; Bilidren; Cholagon; Chologon; Decholin (Miles); Dehychol (Rexall); Deidrocolico Vita; Didrocolo; Erebile; Felacrinos; Procholon (Squibb)
Molecular Formula: C24H34O5
Molecular Weight: 402.52
Percent Composition: C 71.61%, H 8.51%, O 19.87%
Literature References: Prepd from cholic acid by oxidation with CrO3 in glacial acetic acid: Hammarsten in Abderhalden's Handbuch der Biol. Arbeitsmethoden, Abt. I, Teil 6, p 238 (1925); by using chlorine instead of CrO3: Hinkley, Singleton, US 2966499 (1960 to Merck & Co.).
Properties: Bitter crystals from acetone, mp 237°. [a]D20 +26° (c = 1.4 in alc). Soly at 15° (g/l): water 0.18; alcohol 3.3; ether 0.46; chloroform 9.04; benzene 1.04; acetone 7.76; ethyl acetate 7.4; glacial acetic acid 7.42.
Melting point: mp 237°
Optical Rotation: [a]D20 +26° (c = 1.4 in alc)
Derivative Type: Sodium salt
CAS Registry Number: 145-41-5
Additional Names: Sodium dehydrocholate
Trademarks: Carachol; Dycholium; Suprachol
Molecular Formula: C24H33NaO5
Molecular Weight: 424.51
Percent Composition: C 67.90%, H 7.84%, Na 5.42%, O 18.84%
Properties: Very sol in water. pH of aq soln about 9.0.
Therap-Cat: Choleretic.
Keywords: Choleretic.

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