Structural Formula Vector Image
Title: Rescimetol
CAS Registry Number: 73573-42-9
CAS Name: [3b,16b,17a,18b,20a]-18-[[(2E)-3-(4-Hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic acid methyl ester
Additional Names: methyl O-(4-hydroxy-3-methoxycinnamoyl)reserpate
Manufacturers' Codes: CD-3400; WHO-4939
Trademarks: Toscarna (Nippon Chemiphar)
Molecular Formula: C33H38N2O8
Molecular Weight: 590.66
Percent Composition: C 67.10%, H 6.48%, N 4.74%, O 21.67%
Literature References: Analog of rescinnamine. Prepn: BE 782661 corresp to T. Kametani, US 3898215 (1972, 1975 both to Nippon Chemiphar); T. Kametani et al., J. Med. Chem. 15, 686 (1972). Mass spectrum: eidem, J. Chem. Soc. Perkin Trans. 1 1975, 932. Antihypertensive activity: H. Kato et al., Jpn. J. Pharmacol. 27, 87 (1977). Effects on respiration, cardiovascular system, renal function: T. Kamishiro et al., Oyo Yakuri 20, 441 (1980), C.A. 96, 28430w (1982). Toxicity study: T. Fukuda et al., ibid. 18, 71 (1979), C.A. 92, 104392v (1980).
Properties: Pale yellow needles from methanol, mp 259-260°.
Melting point: mp 259-260°
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive.
Status: This monograph has been retired and is no longer subject to revision or update.

Other Monographs:
Vitamin AAllylureaCannabisChromic Formate
MethaqualoneSucrose PolyesterPropyl ChlorocarbonateNauheim Salts (Artificial)
Stannic SelenideSodium MetaperiodateSolanesolFuscin
©2006-2023 DrugFuture->Chemical Index Database