Structural Formula Vector Image
Title: Fenbenicillin
CAS Registry Number: 1926-48-3
CAS Name: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyphenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Additional Names: 3,3-dimethyl-7-oxo-6-(2-phenoxy-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; a-phenoxybenzylpenicillin; 6-(a-phenoxyphenylacetamido)penicillanic acid; 6-(a-phenoxy-a-phenylacetamido)penicillanate; phenbenicillin
Molecular Formula: C22H22N2O5S
Molecular Weight: 426.49
Percent Composition: C 61.96%, H 5.20%, N 6.57%, O 18.76%, S 7.52%
Literature References: Semi-synthetic antibiotic related to penicillin. Prepn: GB 877120 (1961 to Beecham). Bacteriological and pharmacological properties: Rollo, Burley, Br. Med. J. I, 76 (1962).
Derivative Type: Potassium salt
CAS Registry Number: 1177-30-6
Trademarks: Penspek (formerly)
Molecular Formula: C22H21KN2O5S
Molecular Weight: 464.58
Percent Composition: C 56.88%, H 4.56%, K 8.42%, N 6.03%, O 17.22%, S 6.90%
Properties: Powder, mp 88-95°, dec 120-125°. Readily sol in water. LD50 in mice (mg/kg): 225 i.v.; 520 i.p.; 3000 orally (Rollo, Burley).
Melting point: mp 88-95°
Toxicity data: LD50 in mice (mg/kg): 225 i.v.; 520 i.p.; 3000 orally (Rollo, Burley)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.

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