Structural Formula Vector Image
Title: Piperylone
CAS Registry Number: 2531-04-6
CAS Name: 4-Ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl-3H-pyrazol-3-one
Additional Names: 4-ethyl-1-(1-methyl-4-piperidyl)-3-phenyl-3-pyrazolin-5-one; 1-(N-methylpiperid-4-yl)-3-phenyl-4-ethylpyrazol-5-one
Manufacturers' Codes: PR-66
Molecular Formula: C17H23N3O
Molecular Weight: 285.38
Percent Composition: C 71.55%, H 8.12%, N 14.72%, O 5.61%
Literature References: Prepn: Ebnother et al., Helv. Chim. Acta 42, 1201 (1959); Jucker et al., US 2903460 (1959 to Sandoz).
Properties: Crystals from methanol + ether, dec 162-163°. pK1 5.90; pK2 9.15. Very sparingly sol in water. Sol in ethanol, isopropanol, acetone, ethyl acetate.
pKa: pK1 5.90; pK2 9.15
Derivative Type: Hydrobromide
Molecular Formula: C17H23N3O.HBr
Molecular Weight: 366.30
Percent Composition: C 55.74%, H 6.60%, N 11.47%, O 4.37%, Br 21.81%
Properties: Crystals from methanol + ether, dec 194-197°. Sol in water.
Derivative Type: Tartrate
Properties: Crystals from methanol, mp 145-147°.
Melting point: mp 145-147°
NOTE: Ingredient of Palerol (Pelerol) (Sandoz) .
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).
Status: This monograph has been retired and is no longer subject to revision or update.

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