Netobimin
Structural Formula Vector Image
Title: Netobimin
CAS Registry Number: 88255-01-0
CAS Name: 2-[[[(Methoxycarbonyl)amino][[2-nitro-5-(propylthio)phenyl]amino]methylene]amino]ethanesulfonic acid
Additional Names: 2-[[[(methoxycarbonyl)amino][[2-nitro-5-(propylthio)phenyl]imino]methyl]amino]ethanesulfonic acid; methyl [N¢-[2-nitro-5-(propylthio)phenyl]-N-(2-sulfoethyl)amidino]carbamate; N-methoxycarbonyl-N¢-[2-nitro-5-(propylthio)phenyl]-N¢¢-2-(ethylsulfonic acid)guanidine; totabin
Manufacturers' Codes: Sch-32481
Trademarks: Hapadex (Schering)
Molecular Formula: C14H20N4O7S2
Molecular Weight: 420.46
Percent Composition: C 39.99%, H 4.79%, N 13.33%, O 26.64%, S 15.25%
Literature References: Phenylguanidine anthelmintic. Prepn: M. M. Nafissi-Varchei, EP 50286; idem, US 4406893 (1982, 1983 both to Schering). Metabolism in animals: P. Delatour et al., J. Vet. Pharmacol. Ther. 9, 230 (1986). Anthelmintic efficacy in cattle: J. C. Williams et al., Am. J. Vet. Res. 46, 2188 (1985).
Properties: mp 215° (dec).
Melting point: mp 215° (dec)
 
Derivative Type: Sodium salt
Molecular Formula: C14H20N4NaO7S2
Molecular Weight: 443.45
Percent Composition: C 37.92%, H 4.55%, N 12.63%, Na 5.18%, O 25.26%, S 14.46%
Properties: Crystals, mp 150° (dec) (Nafissi-Varchei); also reported as yellow powder, mp 160° (Delatour). uv max (methanol): 225, 347 nm. Sol in water, acetone, methanol, dimethylformamide, DMSO. Insol in ether.
Melting point: mp 150° (dec) (Nafissi-Varchei); mp 160° (Delatour)
Absorption maximum: uv max (methanol): 225, 347 nm
 
Therap-Cat-Vet: Anthelmintic.

Other Monographs:
Mevaldic AcidGadoteridolAlginic AcidDulcin
OxamarinSodium TartrateFerrichromesNimbin
EmbramineSelenocysteinePhosphorusPotassium Iodate
DefibrotideDesonideFenpyroximateGemcitabine
©2006-2023 DrugFuture->Chemical Index Database