Galipine
Structural Formula Vector Image
Title: Galipine
CAS Registry Number: 525-68-8
CAS Name: 2-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methoxyquinoline
Molecular Formula: C20H21NO3
Molecular Weight: 323.39
Percent Composition: C 74.28%, H 6.55%, N 4.33%, O 14.84%
Literature References: From Angostura bark (Cusparia trifoliata Engl., Rutaceae): Körner, Böhringer, Gazz. Chim. Ital. 13, 363 (1883); Tröger, Kroseberg, Arch. Pharm. 250, 494 (1912). Synthesis: Späth, Eberstaller, Ber. 57, 1687 (1924); Späth, Pikl, Ber. 62, 2244 (1929); Schläger, Leeb, Monatsh. Chem. 81, 714 (1950).
Properties: Prismatic needles from alc, mp 116°. Soluble in alcohol, benzene, chloroform, ether; slightly sol in water, petr ether. The salts are more sol than those of cusparine.
Melting point: mp 116°
 
Derivative Type: Hydrochloride tetrahydrate
Molecular Formula: C20H21NO3.HCl.4H2O
Molecular Weight: 431.91
Percent Composition: C 55.62%, H 7.00%, N 3.24%, O 25.93%, Cl 8.21%
Properties: Plates, become anhydr at 100°, mp 165°.
Melting point: mp 165°
 
Derivative Type: Methiodide
Molecular Formula: C20H21NO3.CH3I
Molecular Weight: 465.32
Percent Composition: C 54.20%, H 5.20%, N 3.01%, O 10.32%, I 27.27%
Properties: Yellow needles, mp 146°.
Melting point: mp 146°
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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