Dinotefuran
Structural Formula Vector Image
Title: Dinotefuran
CAS Registry Number: 165252-70-0
CAS Name: N-Methyl-N¢-nitro-N¢¢-[(tetrahydro-3-furanyl)methyl]guanidine
Additional Names: 1-methyl-2-nitro-3-[(3-tetrahydrofuryl)methyl]guanidine
Manufacturers' Codes: MTI-446
Trademarks: Starkle (Mitsui)
Molecular Formula: C7H14N4O3
Molecular Weight: 202.21
Percent Composition: C 41.58%, H 6.98%, N 27.71%, O 23.74%
Literature References: Neonicotinoid insecticide. Prepn: K. Kodaka et al., EP 649845; eidem, US 5434181 (both 1995 to Mitsui Toatsu); T. Wakita et al., Pest Manage. Sci. 59, 1016 (2003). Comprehensive description: eidem, Brighton Crop Prot. Conf. - Pests Dis. 1998, 21-26. Efficacy vs mosquitoes: V. Corbel et al., J. Med. Entomol. 41, 712 (2004).
Properties: White solid from isopropyl ether, mp 94.5-101.5°. Relative density 1.33. Soly in purified water (20°): 54.3 ± 1.3 g/l. Log P (octanol/water): -0.664 (pH 7). LD50 in male, female mice, male, female rats (mg/kg): 2450, 2275, 2804, 2000 orally; in rats (mg/kg): >2000 dermally. LC50 in carp, rainbow trout, crayfish, daphnia (ppm): >1000 (96 hr), >40 (48 hr), 5-10 (48 hr), 1000 (48 hr) (Kodaka).
Melting point: mp 94.5-101.5°
Log P: Log P (octanol/water): -0.664 (pH 7)
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 2450, 2275, 2804, 2000 orally; in rats (mg/kg): >2000 dermally; LC50 in carp, rainbow trout, crayfish, daphnia (ppm): >1000 (96 hr), >40 (48 hr), 5-10 (48 hr)
Use: Insecticide.

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