美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Valacyclovir Hydrochloride	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Valbenazine Tosylate	Capsule (Sprinkle)	I (Basket)	50	0.1 N HCl	900	5, 15, 20, 30 and 45	2024/11/15
Valbenazine Tosylate	Capsule	II (Paddle) with sinker	50	Tier 1: 0.1N HCl; Tier 2: 0.1N HCl containing pepsin (750,000 units per 1000 mL)	900	5, 10, 15, 20 and 30	2017/11/02
Valganciclovir HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Valproic Acid	Capsule			Refer to USP			2009/12/15
Valsartan	Tablet			Refer to USP			2016/07/28
Valsartan	Capsule	II (Paddle)	50	0.067 M Phosphate Buffer, pH 6.8	1000	10, 20, 30 and 45	2004/12/13
Vamorolone	Suspension	II (Paddle)	75	Phosphate Buffer, pH 6.8 w/ 0.5% SLS	900	5, 10, 15, 20, 30, 45, 60 and 90	2025/06/23
Vancomycin hydrochloride	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vandetanib	Tablet	II (Paddle)	50	pH 1.2 Buffer [0.05 M KCl in water, adjust the pH with HCl or NaOH]	1000	5, 10, 15, 20 and 30	2015/06/25
Vardenafil HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vardenafil HCl	Tablet (Orally Disintegrating)	II (Paddle)	50	0.1 N HCl	900	5, 10, 15 and 30	2014/05/15
Varenicline Tartrate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Vemurafenib	Tablet	II (Paddle)	75	1% hexadecyltrimethylammonium bromide (HTAB) in 0.05 M Phosphate Buffer, pH 6.8	900	10, 15, 20, 30 and 45	2015/05/28
Venetoclax	Tablet	III (Reciprocating Cylinder) [Bottom Screen: 200 mesh stainless steel]	20 dpm	Phosphate Buffer, pH 6.8 with 0.4% sodium dodecyl sulfate (SDS) [3 small drops of antifoaming agent may be used]	250	0.25, 0.5, 0.75, 1, 1.5, 2, 3, 3.5 and 4 hours	2016/07/28
Venlafaxine Besylate	Tablet (Extended Release)	II (Paddle with sinker)	50	0.1 M NaCl in water (Degassed)	900	1, 2, 4, 6, 8, 12, 14 and 16 hours	2023/02/09
Venlafaxine HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Venlafaxine HCl	Tablet (Extended Release)			Develop a dissolution method			2023/09/15
Venlafaxine HCl	Capsule (Extended Release)			Develop a dissolution method			2023/09/15
Verapamil HCl	Tablet			Refer to USP			2008/11/04