美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Miglustat	Capsule	I (Basket)	100	0.1 N HCl	1000	10, 20, 30 and 45	2007/01/03
Milnacipran HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Miltefosine	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Minocycline HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Minocycline HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Minocycline HCl	Capsule (Extended Release)	I (Basket- 10 mesh)	100	0.1 N HCl	900	0.25, 0.5, 1.0, 1.5, 2, 3 and 4 hours	2016/06/02
Minocycline HCl	ER Tablets	I (Basket)	100	0.1 N HCl	900	1, 2, 4, 6 hours and until 80% of drug released	2008/01/14
Minocycline HCl	Capsule			Develop a dissolution method			2024/01/03
Minocycline HCl (135 mg and 105 mg)	Tablet (Extended Release)	I (Basket)	100	pH 2.1 Buffer (Degassed)	900	15, 30, 45, 60, 90, 120, 180 and 210	2017/11/02
Minoxidil	Tablet			Refer to USP			2008/04/15
Mirabegron	Tablet (Extended Release)	I (Basket)	100	Phosphate Buffer, pH 6.8	900	1, 3, 5, 7, 8.5, 10 and 12 hours	2013/05/09
Mirabegron	Granules, for Oral Suspension (Extended Release)	II (Paddle)	100	Stage 1: USP Phosphate Buffer (0.036 mol), pH 6.8 (0-4 hours); Stage 2: Phosphate Buffer pH 6.8 (0.108 mol), (after 4 hours)	Stage 1: 500; Stage 2: 1000	0.25, 0.5, 1, 2, 4, 6, 8 and 10 hours	2022/05/12
Mirtazapine	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Mirtazapine	Tablet (Orally Disintegrating (ODT))	II (Paddle)	50	0.1 N HCl	900	5, 10, 15, 20 and 30	2006/03/04
Misoprostol	Tablet			Develop a dissolution method			2023/09/15
Mitapivat Sulfate	Tablet	II (Paddle)	70	100 mM sodium phosphate, pH 6.8, with 0.05% w/w sodium dodecyl sulfate (SLS)	900	5, 10, 15, 20 and 30	2023/03/30
Mitotane	Tablet			Develop a dissolution method			2024/01/03
Mobocertibib Succinate	Capsule	II (Paddle)	50	0.05 M potassium chloride in 0.085 N hydrochloric acid, pH 1.2	500	10, 15, 20, 30, 45 and 60	2023/10/06
Modafinil	Tablet	II (Paddle)	50	0.1 N HCl	900	10, 20, 30, 45 and 60	2004/02/10
Moexipril HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02