FDA药品溶出方法数据库
(FDA-Recommended Dissolution Methods Database)
药品通用名称 剂型 USP溶出装置 速度 溶出介质 介质体积 建议取样时间(分钟) 更新日期
Ibrexafungerp Citrate Tablet II (Paddle) 50 0.1N HCl 900 10, 15, 20, 30 and 45 2023/02/09
Ibrutinib Capsule II (Paddle) 75 3.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 5, 10, 20, 30 and 45 2015/06/25
Ibrutinib Suspension II (Paddle) 25 0.05 M potassium phosphate buffer, pH 6.8, w/ 1.5% (w/v) Tween 20 900 5, 10, 15, 20, 30, 45 and 60 2025/09/08
Ibrutinib (140 and 280 mg) Tablet II (Paddle) 75 3.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 10, 20, 30, 45 and 60 2020/04/02
Ibrutinib (420 and 560 mg) Tablet II (Paddle) 75 6.0% w/v Polysorbate 20 in 50 mM Phosphate Buffer, pH 6.8 900 10, 20, 30, 45 and 60 2020/04/02
Ibuprofen Tablet (Chewable) II (Paddle) 50 0.05 M Phosphate Buffer, pH 7.2 900 10, 20, 30 and 45 2004/02/04
Ibuprofen Capsule (Soft-Gelatin/Liquid Fill) I (Basket) 150 50mM Phosphate Buffer, pH 7.2 900 5, 10, 20, 30 and 45 2013/05/09
Ibuprofen Tablet Refer to USP 2007/07/25
Ibuprofen Suspension Refer to USP 2008/11/04
Ibuprofen Suspension/Drop II (Paddle) 50 Phosphate Buffer, pH 7.2 900 5, 10, 15 and 20 2008/11/04
Ibuprofen Potassium Capsule (Soft-Gelatin/Liquid Fill) I (Basket) 150 Phosphate Buffer, pH 7.2 900 5, 10, 20 and 30 2004/02/04
Ibuprofen Sodium Capsule I (Basket) 150 Phosphate Buffer, pH 7.2 900 5, 10, 15, 20 and 30 2015/06/25
Ibuprofen/Diphenhydramine Capsule I (Basket) 100 Phosphate Buffer (200 mM), pH7.2 900 10, 20, 30 and 45 2007/01/03
Ibuprofen/Oxycodone HCl Tablet I (Basket) 100 Phosphate buffer, pH 7.2 500 10, 20, 30 and 45 2007/04/09
Ibuprofen/Phenylephrine HCl Tablet II (Paddle) 50 50 mM Potassium Phosphate Buffer, pH 6.5, (degassed) 900 10, 15, 20, 30 and 45 2012/01/05
Ibuprofen/Pseudoephedrine HCl Capsule I (Basket) 150 Tier 1: 0.05 M phosphate buffer, pH 7.2 Tier 2: 0.05 M phosphate buffer, pH 7.2 with NMT 1750 USP protease units/L of 1 X USP pancreatin 900 10, 20, 30 and 45 2006/03/04
Ibuprofen/Pseudoephedrine HCl Suspension II (Paddle) 50 0.05 M Phosphate Buffer, pH 7.2 900 5, 10, 15 and 30 2004/02/04
Icotrokinra HCl Tablet II (Paddle) 50 0.1 M Citrate Buffer, pH 4.5 500 5, 10, 15, 20, 30, 45 and 60 2026/05/22
Idelalisib Tablet II (Paddle) 75 0.01 N HCl 750 5, 10, 15, 20 and 30 2015/08/27
Iloperidone Tablet II (Paddle) 50 0.1 N HCl 500 5, 10, 15, 30, 45 and 60 2010/08/05

数据库说明:

当前数据更新日期:2026年06月14日。
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