美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Fenofibrate	Capsule (Micronized)			Develop a dissolution method			2023/09/15
Fenofibrate (40 mg and 120 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibrate (48 mg and 145 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibrate (54 mg and 160 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibric Acid	Tablet	II (Paddle)	75	Phosphate buffer, pH 6.8	900	5, 15, 30, 45 and 60	2010/08/05
Fenoprofen Calcium	Capsule			Refer to USP			2008/11/25
Fentanyl	Transdermal	VII (Reciprocating holder)- cylinder.	30 cycles per minute. amplitude of about 2m.	Equimolar mixture of 0.005 M phosphoric acid solution, and 0.005 M sodium phosphate, monobasic monohydrate (pH ~ 2.6). at 32° C. Change the test samples into fresh pre-equilibrated release medium at the time points indicated. Remove the protective liner and place the film onto a piece of nylon netting with adhesive facing the net. Secure the netting and transdermal system using nylon tie wraps at the top and bottom of the cylinder on the holder. The adhesive side faces towards the media.	250 mL for the 75 and 100 mcg/hr, 200 mL for the 50 mcg/hr and 150 mL for the 25 and 12.5 mcg/hr dosage strength.	0.5, 1, 2, 4 and 24 hours	2011/06/09
Fentanyl Citrate	Tablet (Sublingual)	II (Paddle)	50	Phosphate Buffer, pH 6.8	500	1, 3, 5, 7, 10, 15 and 20	2013/08/15
Fentanyl Citrate	Lozenges	II (Paddle)	175	0.1 M Phosphate Buffer, pH 4.5	500	5, 10, 20, 30 and 40	2009/05/20
Fentanyl Citrate (0.1 mg and 0.4 mg)	Tablet (Buccal)	II (Paddle) small volume dissolution apparatus	100	Phosphate Buffered Saline solution, pH 7.0	100	3, 5, 7.5, 10, 15 and 20	2009/11/20
Fentanyl Citrate (0.2 mg, 0.3 mg, 0.6 mg and 0.8 mg)	Tablet (Buccal)	II (Paddle) small volume dissolution apparatus	100	Phosphate Buffered Saline solution, pH 7.0	200	3, 5, 7.5, 10, 15 and 20	2009/11/20
Fentanyl Citrate (0.2 mg, 0.4 mg, 0.6 mg and 0.8 mg)	Film (Buccal)	I (Basket) 100 mL dissolution vessel	100	25-mM Phosphate Buffer, pH 6.4	60	5, 10, 15, 20, 30 and 45	2009/12/15
Fentanyl Citrate (1.2 mg)	Film (Buccal)	I (Basket) 100 mL dissolution vessel	100	25-mM Phosphate Buffer, pH 6.4	100	5, 10, 15, 20, 30 and 45	2009/12/15
Ferric Citrate	Tablet	II (Paddle)	100	EDTA media ( 2.0 grams of EDTA Na2 2H2O to 1000 mL of purified water)	900	10, 20, 30, 45 and 60	2015/08/27
Ferric Maltol	Capsule	II (Paddle with sinker)	75	Tier 1: KCl/HCl Buffer, pH 1.2; Tier 2: KCl/HCl Buffer pH 1.2, with pepsin	1000	5, 10, 20, 30 and 45	2020/01/30
Ferrous Fumarate	Tablet			Refer to USP			2016/03/17
Fesoterodine Fumarate	Tablet (Extended Release)	II (Paddle) with sinker	75	Phosphate Buffer, pH 6.8	900	1, 2, 4, 6, 8, 10, 12, 16 and 20 hours	2013/08/15
Fexinidazole	Tablet	II (Paddle)	75	0.1 N HCl with 3% w/v SLS	2000	10, 20, 30, 40, 50 and 60	2023/05/18
Fexofenadine HCl	Tablet	II (Paddle)	50	0.001 N HCl	900	5, 10, 20, 30 and 45	2004/02/19
Fexofenadine HCl	Capsule			Develop a dissolution method			2023/09/15