美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Ferric Citrate	Tablet	II (Paddle)	100	EDTA media ( 2.0 grams of EDTA Na2 2H2O to 1000 mL of purified water)	900	10, 20, 30, 45 and 60	2015/08/27
Ferric Maltol	Capsule	II (Paddle with sinker)	75	Tier 1: KCl/HCl Buffer, pH 1.2; Tier 2: KCl/HCl Buffer pH 1.2, with pepsin	1000	5, 10, 20, 30 and 45	2020/01/30
Ferrous Fumarate	Tablet			Refer to USP			2016/03/17
Fesoterodine Fumarate	Tablet (Extended Release)	II (Paddle) with sinker	75	Phosphate Buffer, pH 6.8	900	1, 2, 4, 6, 8, 10, 12, 16 and 20 hours	2013/08/15
Fexinidazole	Tablet	II (Paddle)	75	0.1 N HCl with 3% w/v SLS	2000	10, 20, 30, 40, 50 and 60	2023/05/18
Fexofenadine HCl	Tablet (Orally Disintegrating)	II (Paddle)	50	0.001 N HCl	500	5, 10, 15, 30 and 45	2008/09/03
Fexofenadine HCl	Suspension	II (Paddle)	50	0.001 N HCl	900	10, 20, 30 and 45	2008/11/25
Fexofenadine HCl	Tablet	II (Paddle)	50	0.001 N HCl	900	5, 10, 20, 30 and 45	2004/02/19
Fexofenadine HCl	Capsule			Develop a dissolution method			2023/09/15
Fexofenadine HCl/Pseudoephedrine HCl	Tablet (Extended Release)			Refer to USP			2009/04/02
Fezolinetant	Tablet			Refer to FDA's Dissolution Guidance, 2018			2024/08/05
Fidaxomicin	For Oral Suspension			Develop a dissolution method			2023/09/15
Fidaxomicin	Tablet			Develop a dissolution method			2023/09/15
Finafloxacin	Otic Suspension			Develop a method to characterize in vitro release			2016/03/17
Finasteride	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Finasteride; Tadalafil	Capsule			Develop a dissolution method			2024/02/05
Finerenone	Tablet	II (Paddle)	75	Acetate Buffer, pH 4.5 (for 10 mg strength) and Acetate Buffer, pH 4.5 with 0.1% polysorbate 20 (for 20 mg strength)	900	5, 10, 15, 20 and 30	2023/02/09
Fingolimod	Capsule	I (Basket)	100	0.1 N HCl with 0.2% SDS (sodium dodecyl sulfate)	500	5, 10, 15, 20 and 30	2013/08/15
Fingolimod Lauryl Sulfate	Tablet, Orally Disintegrating	II (Paddle) with sinker	50	0.1 N HCl with 0.2% sodium dodecyl sulfate (SDS)	500	5, 10, 15, 20, 25, 30 and 45	2023/11/30
Flavoxate HCl	Tablet	I (Basket)	100	0.1 N HCl	900	5, 10, 20 and 30	2004/01/29