美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Famotidine/Ibuprofen	Tablet	II (Paddle)	50	0.05 M Phosphate Buffer, pH 7.2	900	5, 10, 15, 20, 30 and 45	2013/08/15
Febuxostat	Tablet	II (Paddle)	75	0.05 M Phosphate Buffer, pH 6.0	900	5, 10, 15, 20 and 30	2013/08/15
Fedratinib HCl	Capsule	I (Basket)	50	0.1 N HCl	900	5, 10, 15, 20 and 30	2021/08/19
Felbamate	Tablet			Develop a dissolution method			2024/01/03
Felbamate	Suspension			Develop a dissolution method			2023/09/15
Felodipine	Tablet (Extended Release)			Develop a dissolution method			2024/01/03
Fenofibrate	Capsule	II (Paddle)	75	Phosphate Buffer w/ 2% Tween 80 and 0.1% pancreatin, pH 6.8	900	15, 30, 45, 60, 90 and 120	2008/02/19
Fenofibrate	Capsule (Micronized)			Develop a dissolution method			2023/09/15
Fenofibrate (40 mg and 120 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibrate (48 mg and 145 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibrate (54 mg and 160 mg)	Tablet			Develop a dissolution method			2023/09/15
Fenofibric Acid	Tablet	II (Paddle)	75	Phosphate buffer, pH 6.8	900	5, 15, 30, 45 and 60	2010/08/05
Fenoprofen Calcium	Capsule			Refer to USP			2008/11/25
Fentanyl	Transdermal	VII (Reciprocating holder)- cylinder.	30 cycles per minute. amplitude of about 2m.	Equimolar mixture of 0.005 M phosphoric acid solution, and 0.005 M sodium phosphate, monobasic monohydrate (pH ~ 2.6). at 32° C. Change the test samples into fresh pre-equilibrated release medium at the time points indicated. Remove the protective liner and place the film onto a piece of nylon netting with adhesive facing the net. Secure the netting and transdermal system using nylon tie wraps at the top and bottom of the cylinder on the holder. The adhesive side faces towards the media.	250 mL for the 75 and 100 mcg/hr, 200 mL for the 50 mcg/hr and 150 mL for the 25 and 12.5 mcg/hr dosage strength.	0.5, 1, 2, 4 and 24 hours	2011/06/09
Fentanyl Citrate	Tablet (Sublingual)	II (Paddle)	50	Phosphate Buffer, pH 6.8	500	1, 3, 5, 7, 10, 15 and 20	2013/08/15
Fentanyl Citrate	Lozenges	II (Paddle)	175	0.1 M Phosphate Buffer, pH 4.5	500	5, 10, 20, 30 and 40	2009/05/20
Fentanyl Citrate (0.1 mg and 0.4 mg)	Tablet (Buccal)	II (Paddle) small volume dissolution apparatus	100	Phosphate Buffered Saline solution, pH 7.0	100	3, 5, 7.5, 10, 15 and 20	2009/11/20
Fentanyl Citrate (0.2 mg, 0.3 mg, 0.6 mg and 0.8 mg)	Tablet (Buccal)	II (Paddle) small volume dissolution apparatus	100	Phosphate Buffered Saline solution, pH 7.0	200	3, 5, 7.5, 10, 15 and 20	2009/11/20
Fentanyl Citrate (0.2 mg, 0.4 mg, 0.6 mg and 0.8 mg)	Film (Buccal)	I (Basket) 100 mL dissolution vessel	100	25-mM Phosphate Buffer, pH 6.4	60	5, 10, 15, 20, 30 and 45	2009/12/15
Fentanyl Citrate (1.2 mg)	Film (Buccal)	I (Basket) 100 mL dissolution vessel	100	25-mM Phosphate Buffer, pH 6.4	100	5, 10, 15, 20, 30 and 45	2009/12/15