Structural Formula Vector Image
Title: Viminol
CAS Registry Number: 21363-18-8
CAS Name: a-[[Bis(1-methylpropyl)amino]methyl]-1-[(2-chlorophenyl)methyl]-1H-pyrrole-2-methanol
Additional Names: 1-(o-chlorobenzyl)-a-[(di-sec-butylamino)methyl]pyrrole-2-methanol; 1-[a-(N-o-chlorobenzyl)pyrryl]-2-di-sec-butylaminoethanol; diviminol
Manufacturers' Codes: Z-424
Molecular Formula: C21H31ClN2O
Molecular Weight: 362.94
Percent Composition: C 69.49%, H 8.61%, Cl 9.77%, N 7.72%, O 4.41%
Literature References: Prepn: U. M. Teotino, D. Della Bella, ZA 6702732, eidem, US 3539589 (1970 to Whitefin Holding). Synthesis and metabolic fate of 14C-viminol: Cameron et al., Arzneim.-Forsch. 23, 708 (1973). Viminol possesses 3 asymmetric carbon atoms and thus is composed of 6 stereoisomers. Role of stereoisomers in determining specific pharmacological effects: D. Della Bella et al., Nature New Biol. 241, 282 (1973). Additional pharmacology data: M. Babbini et al., Eur. J. Pharmacol. 23, 137 (1973). Review: D. Della Bella, Boll. Chim. Farm. 111, 5-19 (1972).
Properties: bp0.1 mm 160-165°.
Boiling point: bp0.1 mm 160-165°
Derivative Type: p-Hydroxybenzoate
CAS Registry Number: 23784-10-3
Trademarks: Dividol (Zambon)
Molecular Formula: C21H31ClN2O.C7H6O3
Molecular Weight: 501.06
Percent Composition: C 67.12%, H 7.44%, Cl 7.08%, N 5.59%, O 12.77%
Properties: mp 128-130° (dec). LD50 i.p. in rats: 205.9 mg/kg (Babbini).
Melting point: mp 128-130° (dec)
Toxicity data: LD50 i.p. in rats: 205.9 mg/kg (Babbini)
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).

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