Toluene 2,4-Diisocyanate
Structural Formula Vector Image
Title: Toluene 2,4-Diisocyanate
CAS Registry Number: 584-84-9
CAS Name: 2,4-Diisocyanato-1-methylbenzene
Additional Names: 2,4-diisocyanatotoluene; 2,4-tolylene diisocyanate; TDI
Trademarks: Nacconate 100 (Allied)
Molecular Formula: C9H6N2O2
Molecular Weight: 174.16
Percent Composition: C 62.07%, H 3.47%, N 16.08%, O 18.37%
Literature References: Usually prepd from toluene-2,4-diamine and phosgene. Review: Astle, Industrial Organic Nitrogen Compounds (New York, 1961) pp 284-313; Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 831-835.
Properties: Liquid at room temperature. Sharp, pungent odor. mp 19.5-21.5°. d420 liq 1.2244. bp760 251°; bp11 126°. Darkens on exposure to sunlight. Reacts with water with evolution of carbon dioxide. Flash pt, open cup: 132°C (270°F). Misc with alcohol (decompn), diglycol monomethyl ether, ether, acetone, carbon tetrachloride, benzene, chlorobenzene, kerosene, olive oil. Concd alkaline compds such as NaOH or tert-amines may cause run-away polymerization.
Melting point: mp 19.5-21.5°
Boiling point: bp760 251°; bp11 126°
Flash point: Flash pt, open cup: 132°C (270°F)
Density: d420 liq 1.2244
CAUTION: Potential symptoms of overexposure are irritation of eyes, skin, nose and throat; choking, paroxysmal cough; chest pain, retrosternal soreness; nausea, vomiting and abdominal pain; bronchitis, bronchospasm, pulmonary edema; dyspnea, asthma; conjunctivitis, lacrimation; dermatitis, skin sensitization. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 312. See also Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 414. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-256.
Use: In the manuf of polyurethane foams and other elastomers.

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