Structural Formula Vector Image
Title: Suclofenide
CAS Registry Number: 30279-49-3
CAS Name: 3-Chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)benzenesulfonamide
Additional Names: 3-chloro-4-(phenylsuccinimido)benzenesulfonamide; 1-(a-phenylsuccinimido)-2-chloro-4-sulfamoylbenzene; 1-(2-chloro-4-sulfamoylphenyl)-3-phenylsuccinimide
Manufacturers' Codes: CGP-8426; GS-385
Trademarks: Sulfalepsin (Geistlich)
Molecular Formula: C16H13ClN2O4S
Molecular Weight: 364.80
Percent Composition: C 52.68%, H 3.59%, Cl 9.72%, N 7.68%, O 17.54%, S 8.79%
Literature References: Anti-epileptic agent. Prepn: R. W. Pfirrmann, BE 752109; idem, US 3789056 (1970, 1974 both to Geistlich). Pharmacology: Arzneim.-Forsch. 27, 1942 (1977). HPLC determn in biological materials: F. Mikes et al., ibid. 29, 1583 (1979).
Properties: Crystals from methanol/ether-petroleum ether, mp 205-207°. LD50 orally in mice: >5000 mg/kg (Mikes).
Melting point: mp 205-207°
Toxicity data: LD50 orally in mice: >5000 mg/kg (Mikes)
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.
Status: This monograph has been retired and is no longer subject to revision or update.

Other Monographs:
Succinyl ChlorideTilidinePindololStenbolone
Belleau's ReagentCefuroximeEthylestrenolEthylbenzene
©2006-2023 DrugFuture->Chemical Index Database