Structural Formula Vector Image
Title: Pipotiazine
CAS Registry Number: 39860-99-6
CAS Name: 10-[3-[4-(2-Hydroxyethyl)-1-piperidinyl]propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
Additional Names: 2-[1-[3-[2-[(dimethylamino)sulfonyl]-10H-phenothiazin-10-yl]propyl]-4-piperidinyl]ethanol; pipothiazine
Manufacturers' Codes: RP-19366
Trademarks: Piportil (Specia)
Molecular Formula: C24H33N3O3S2
Molecular Weight: 475.67
Percent Composition: C 60.60%, H 6.99%, N 8.83%, O 10.09%, S 13.48%
Literature References: Prepn: FR M7835 (1970 to Rhône-Poulenc), C.A. 78, 43499x (1973). Pharmacokinetics: P. J. De Schepper et al., Arzneim.-Forsch. 29, 1056 (1979); and HPLC determn in plasma: D. A. Ogden et al., J. Pharm. Biomed. Anal. 7, 1273 (1989). Series of articles on pharmacology and clinical use: Acta Psychiat. Scand., Suppl. 241, 9-138 (1973). Toxicity: L. Julou et al., ibid. 9.
Properties: LD50 in mice (mg/kg): 108 i.p.; 360 s.c.; 440 orally (Julou).
Toxicity data: LD50 in mice (mg/kg): 108 i.p.; 360 s.c.; 440 orally (Julou)
Derivative Type: Palmitic ester
CAS Registry Number: 37517-26-3
Additional Names: Pipotiazine palmitate
Manufacturers' Codes: RP-19552
Trademarks: Piportil L4 (Specia)
Molecular Formula: C40H63N3O4S2
Molecular Weight: 714.08
Percent Composition: C 67.28%, H 8.89%, N 5.88%, O 8.96%, S 8.98%
Derivative Type: Undecylenic ester
CAS Registry Number: 22178-11-6
Additional Names: Pipotiazine undecylenate
Manufacturers' Codes: RP-19551
Trademarks: Piportil M2 (Specia)
Molecular Formula: C35H51N3O4S2
Molecular Weight: 641.93
Percent Composition: C 65.49%, H 8.01%, N 6.55%, O 9.97%, S 9.99%
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.

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