Naepaine
Structural Formula Vector Image
Title: Naepaine
CAS Registry Number: 2188-67-2
CAS Name: 2-(Pentylamino)ethanol 4-aminobenzoate (ester)
Additional Names: p-aminobenzoic acid 2-n-pentylaminoethyl ester; p-aminobenzoic acid 2-n-amylaminoethyl ester; 2-n-amylaminoethyl p-aminobenzoate; 2-n-pentylaminoethyl p-aminobenzoate
Trademarks: Amylsine
Molecular Formula: C14H22N2O2
Molecular Weight: 250.34
Percent Composition: C 67.17%, H 8.86%, N 11.19%, O 12.78%
Literature References: Prepn: Goldberg, Whitmore, J. Am. Chem. Soc. 59, 2280 (1937). Prepn of dimorphic cryst forms: Kreider, Menotti, ibid. 64, 1227 (1942).
Properties: Solid, mp 66°.
Melting point: mp 66°
 
Derivative Type: Hydrochloride
Molecular Formula: C14H23ClN2O2
Molecular Weight: 286.80
Percent Composition: C 58.63%, H 8.08%, Cl 12.36%, N 9.77%, O 11.16%
Properties: Dimorphic crystals. Rectangular plates, mp 153.5°; rods, mp 176°. Bitter taste followed by a sense of numbness. Sol in water; sparingly sol in alcohol; insol in ether, chloroform, benzene.
Melting point: mp 153.5°; mp 176°
 
Therap-Cat: Hydrochloride as local anesthetic.
Therap-Cat-Vet: Topical anesthetic (ocular).
Keywords: Anesthetic (Local).
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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