Mercumallylic Acid
Structural Formula Vector Image
Title: Mercumallylic Acid
CAS Registry Number: 86-36-2
CAS Name: [3-(3-Carboxy-2-oxo-2H-1-benzopyran-8-yl)-2-methoxypropyl]hydroxymercurate(1-) hydrogen
Additional Names: [3-[3-(hydroxymercuri)-2-methoxypropyl]salicylidene]malonic acid d-lactone; 8-[3-(hydroxymercuri)-2-methoxypropyl]-2-oxo-2H-1-benzopyran-3-carboxylic acid; 8-(2-methoxy-3-hydroxymercuripropyl)coumarin-3-carboxylic acid; 8-[3-(hydroxymercuri)-2-methoxypropyl]-3-carboxycoumarin; 8-[3-(hydroxymercuri)-2-methoxypropyl]coumarin-3-carboxylic acid
Molecular Formula: C14H14HgO6
Molecular Weight: 478.85
Percent Composition: C 35.12%, H 2.95%, Hg 41.89%, O 20.05%
Literature References: Prepn: A. Schlesinger et al., US 2667442 (1954 to Endo); L. H. Werner, C. R. Scholz, J. Am. Chem. Soc. 76, 2453 (1954). Toxicology of mercumatalin sodium: H. Blumberg et al., J. Pharmacol. Exp. Ther. 105, 336 (1952).
Properties: Powder, bitter taste. mp 155-160° (Schlesinger); mp 197° (Werner, Scholz). One gram dissolves in about 4.2 parts of 1N NaOH. Slightly sol in acetic acid. Very slightly sol in water, alcohol, chloroform. Practically insol in ether.
Melting point: mp 155-160° (Schlesinger); mp 197° (Werner, Scholz)
Derivative Type: Sodium salt compd with theophylline
CAS Registry Number: 8018-15-3
Additional Names: Mercumatilin sodium
Trademarks: Cumertilin Sodium (Endo)
Molecular Formula: C21H21HgN4NaO8
Molecular Weight: 680.99
Percent Composition: C 37.04%, H 3.11%, Hg 29.46%, N 8.23%, Na 3.38%, O 18.80%
Properties: Dry, light yellow powder. Very sol in water. LD50 in rats (mg Hg/kg): 9.8 i.v.; 238 orally (Blumberg).
Toxicity data: LD50 in rats (mg Hg/kg): 9.8 i.v.; 238 orally (Blumberg)
Therap-Cat: Diuretic.

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