Structural Formula Vector Image
Title: Leteprinim
CAS Registry Number: 138117-50-7
CAS Name: 4-[[3-(1,6-Dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl]amino]benzoic acid
Molecular Formula: C15H13N5O4
Molecular Weight: 327.29
Percent Composition: C 55.05%, H 4.00%, N 21.40%, O 19.55%
Literature References: Synthetic purine derivative with neuroprotective effects. Prepn: A. J. Glasky, WO 9114434 (1991); idem, US 5091432 (1992). Effect on working memory in mice: idem et al., Pharmacol. Biochem. Behav. 47, 325 (1994). Mode of action study: P. J. Middlemiss et al., Neurosci. Lett. 199, 131 (1995). Mechanism of brain efflux: R. Yan, E. M. Taylor, Drug Metab. Dispos. 30, 513 (2002). Reviews of pharmacology: M. P. Rathbone et al., Drug Dev. Res. 45, 356-372 (1998); idem et al., Expert Opin. Invest. Drugs 8, 1255-1262 (1999).
Properties: White solid, mp 319-321°.
Melting point: mp 319-321°.
Derivative Type: Potassium salt
CAS Registry Number: 192564-13-9
Manufacturers' Codes: AIT-082
Trademarks: Neotrofin (Spectrum)
Molecular Formula: C15H13KN5O4
Molecular Weight: 366.39
Percent Composition: C 49.17%, H 3.58%, K 10.67%, N 19.11%, O 17.47%
Therap-Cat: Nootropic.
Keywords: Nootropic.

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