Structural Formula Vector Image
Title: Lachesine
CAS Registry Number: 1164-38-1
CAS Name: N-Ethyl-2-[(hydroxydiphenylacetyl)oxy]-N,N-dimethylethanaminium chloride
Additional Names: ethyl(2-hydroxyethyl)dimethylammonium chloride benzilate
Manufacturers' Codes: E-3
Molecular Formula: C20H26ClNO3
Molecular Weight: 363.88
Percent Composition: C 66.01%, H 7.20%, Cl 9.74%, N 3.85%, O 13.19%
Literature References: Prepn: Ford-Moore, Ing, J. Chem. Soc. 1947, 55. Pharmacology: H. R. Ing et al., J. Pharmacol. Exp. Ther. 85, 85 (1945). Muscarinic receptor agonist: F. Roberts, R. P. Stephenson, Br. J. Pharmacol. 57, 395 (1976); D. A. Brown, S. Fatherazi, ibid. 59, 500P (1977); N. J. M. Birdsall et al., Mol. Pharmacol. 14, 723 (1978).
Properties: Crystals from ethanol + acetone, mp 213°. LD50 in mice (mg/20 g): 0.8 i.p.; 3.2 s.c.; 20.0 orally (Ing).
Melting point: mp 213°
Toxicity data: LD50 in mice (mg/20 g): 0.8 i.p.; 3.2 s.c.; 20.0 orally (Ing)
Status: This monograph has been retired and is no longer subject to revision or update.

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