Structural Formula Vector Image
Title: Ipriflavone
CAS Registry Number: 35212-22-7
CAS Name: 7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one
Additional Names: 7-isopropoxy-3-phenyl-4H-1-benzopyran-4-one; 7-isopropoxy-3-phenylchromone; 7-isopropoxyisoflavone
Manufacturers' Codes: FL-113; TC-80
Trademarks: Iprosten (Takeda); Osten (Takeda); Osteofix (Chiesi); Yambolap (Chinoin)
Molecular Formula: C18H16O3
Molecular Weight: 280.32
Percent Composition: C 77.12%, H 5.75%, O 17.12%
Literature References: Isoflavone derivative with anti-anginal and anti-osteopenic activity. Prepn: L. Feuer et al., DE 2125245 (1971 to Chinoin), C.A. 76, 72407e (1972). Use as anabolic in animals: eidem, US 3833730; in humans; eidem, US 3949085 (1974, 1976 both to Chinoin). Cardiovascular properties in stable angina: V. Grubich et al., Lancet 1, 211 (1979). Cardiological effects in animals: L. Feuer et al., Arzneim.-Forsch. 31, 953 (1981). Metabolism and disposition in rats: K. Yoshida et al., Radioisotopes 34, 612, 618 (1985). Effect in rats on estrogen-stimulated calcitonin secretion: I. Yamazaki, Life Sci. 38, 757 (1986); I. Yamazaki, M. Kinoshita, ibid. 1535; on glucocorticoid-induced osteoporosis: I. Yamazaki et al., ibid. 951.
Properties: Crystals from acetone, mp 115-117°.
Melting point: mp 115-117°
Therap-Cat: Calcium regulator.
Keywords: Calcium Regulator.

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