Hexethal Sodium
Structural Formula Vector Image
Title: Hexethal Sodium
CAS Registry Number: 144-00-3
CAS Name: 5-Ethyl-5-hexyl-2,4,6(1H,3H,5H)-pyrimidinetrione monosodium salt
Additional Names: sodium 5-ethyl-5-hexylbarbiturate
Trademarks: Ortal Sodium; Hebaral
Molecular Formula: C12H19N2NaO3
Molecular Weight: 262.28
Percent Composition: C 54.95%, H 7.30%, N 10.68%, Na 8.77%, O 18.30%
Literature References: Prepn: A. W. Dox, US 1624546. Anesthetic properties and toxicity data: C. M. Gruber, J. T. Brundage, J. Pharmacol. Exp. Ther. 60, 439 (1937).
Properties: White or slightly yellowish powder, mp 126°. Bitter taste. Very sol in water; sol in alcohol. Insol in ether, benzene. Aq solns are alkaline to litmus. Aq solns are unstable and dec on standing. Boiling evolves ammonia and causes precipitation of a solid. MLD i.p. in rats: 240-250 mg/kg (Gruber, Brundage).
Melting point: mp 126°
Toxicity data: MLD i.p. in rats: 240-250 mg/kg (Gruber, Brundage)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative; hypnotic.
Therap-Cat-Vet: Sedative; hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.

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