Structural Formula Vector Image
Title: Hexaminolevulinate
CAS Registry Number: 140898-97-1
CAS Name: 5-Amino-4-oxopentanoic acid hexyl ester
Additional Names: 5-aminolevulinic acid hexyl ester; hexyl 5-aminolevulinate
Molecular Formula: C11H21NO3
Molecular Weight: 215.29
Percent Composition: C 61.37%, H 9.83%, N 6.51%, O 22.29%
Literature References: Prodrug of d-aminolevulinic acid, q.v.; induces production of intracellular protoporphyrin IX. Prepn: H. Takeya, JP Kokai 92 9360 (1992 to Cosmo Sogo Kenkyusho); and use as photosensitizer: K. E. Gierskcky et al., WO 9628412 (1996 to Norwegian Radium Res. Found.); eidem, US 6034267 (2000 to PhotoCure). Synthesis and pharmacology: C. J. Whitaker et al., Anti-Cancer Drug Des. 15, 161 (2000). Clinical evaluation for photodetection of bladder cancer: N. Lange et al., Br. J. Cancer 80, 185 (1999).
Derivative Type: Hydrochloride
CAS Registry Number: 140898-91-5
Manufacturers' Codes: P-1206
Trademarks: Hexvix (PhotoCure)
Molecular Formula: C11H21NO3.HCl
Molecular Weight: 251.75
Percent Composition: C 52.48%, H 8.81%, N 5.56%, O 19.07%, Cl 14.08%
Properties: Crystals from methanol/ethyl acetate, mp 94°.
Melting point: mp 94°
Therap-Cat: Diagnostic aid (fluorescence imaging agent).
Keywords: Diagnostic Aid.

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